Comparison of patients with Beh�et's disease in the 1980s and 1990s*1

Yoshida, Atsushi; Kawashima, Hidetoshi; Motoyama, Yuta; Shibui, Hirobumi; Kaburaki, Toshikatsu; Shimizu, Kazuyuki; Andō, Kazuhiko; Hijikata, Kiyono; Izawa, Yasuho; Hayashi, Katsuro; Numaga, Jiro; Fujino, Yujiro; Masuda, Kohji; Araie, Makoto

doi:10.1016/j.ophtha.2003.07.018

Cited by 112 publications

(101 citation statements)

References 15 publications

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“…Ocular manifestations include anterior uveitis, retinal vasculitis, retinal infiltrates, haemorrhages and oedema, and inflammatory retinal vein occlusion [9]. Ocular inflammation occurs in about 50% of patients with Behçet’s disease and may lead to severe visual loss [10, 11]. Secondary optic atrophy (from papilloedema due to dural sinus thrombosis), and consecutive optic atrophy (i.e.…”

Section: Discussionmentioning

confidence: 99%

Acute Optic Neuropathy in Patients with Behçet’s Disease

Voros¹,

Sandhu²,

Pandit³

2006

Ophthalmologica

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Although acute optic neuropathy has been rarely reported in patients with Behçet’s disease, a detailed description of its clinical course is lacking. We report in detail the course of acute optic neuropathy in two patients with Behçet’s disease. Our experience suggests that it can be bilateral, can affect both eyes simultaneously, and can be recurrent. The severity of the visual loss and its recovery can be very variable even in the same patient. Early recognition of this entity and treatment with high-dose systemic corticosteroids may limit the degree of permanent visual loss. However, the optimal treatment has not been established.

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Section: Discussionmentioning

confidence: 99%

Acute Optic Neuropathy in Patients with Behçet’s Disease

Voros¹,

Sandhu²,

Pandit³

2006

Ophthalmologica

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“…Various epidemiological studies have been performed in different regions and ethnic populations (5)(6)(7)(8)(9)(10)(11)(12). Furthermore, changing patterns of intraocular inflammatory diseases have been reported (12)(13)(14)(15)(16). Knowledge about the different types and etiology of uveitis in various populations is of importance in order to aid the clinician to make an appropriate investigation, differential diagnosis, and treatment.…”

Section: Introductionmentioning

confidence: 99%

Epidemiology of uveitis in a referral hospital in Turkey

Özdal¹,

Yazıcı²,

Tüfek³

et al. 2014

Turk J Med Sci

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A series of (E) -3- (3-(2,3-dihydro-3-methyl-2-oxo-3 H -benzoxazole-6-yl)-1-phenyl-1 H -pyrazole-4-yl)acrylamides (7a-k) were synthesized and evaluated for their in vitro inhibitory activities on COX-1 and COX-2 isoforms using a human whole blood assay as well as their antiplatelet profile against human platelet aggregation using arachidonic acid as agonists. Among the synthesized derivatives 7a-k, especially compound 7g exhibited dual anti-inflammatory and antiplatelet activity with selective COX-2 inhibition.

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“…17,18 Behçet hastalığı ile ilişkili optik sinir tutulumu literatürde yaygın olarak tanımlanmak-tadır, ancak tanımlanan tutulumlar genellikle dural sinüs trombozlarına bağlı papilödemi ve sonrasında gelişen sekonder optik atrofiler ya da ağır retinal tutuluma ardıl gelişen optik atrofiler şeklindedir. 9,20 Primer optik sinir tutulumunun sıklığı tam olarak KAYNAKLAR bilinmemekle birlikte, Lamari ve ark.nın yaptığı ça-lışmada, 400 Behçet hastasının 148'inde optik sinir tutulumu saptanmış, ancak bunlardan sadece 13'ünde primer optik sinir tutulumu olduğu gö-rülmüştür ve oran %9 olarak verilmiştir. 21 Primer olarak optik sinir tutulumu Behçet hastalığı için karakteristik olmasa da olgu sunumları olarak çeşitli çalışmalarda gösterilmiştir.…”

Section: Discussionunclassified