Comparison of parenteral ciprofloxacin with clindamycin-gentamicin in the treatment of pelvic infection

Oral and Intramuscular Treatment Options for Early Postpartum Endometritis in Low-Resource Settings

“…46,59 In phase II, 530 articles were reviewed, of which 38 provided genus or speciated information related to organisms identified by endometrial culture at the time of diagnosis (before antibiotic treatment). We identified 38 studies 17,18,21,22,25,29,30,33,34,36,37,40,42,44,46,48,49,51,55,[57][58][59][60][61][62][63][64][65][66][67][68][69][70][71][72][73] that reported pathogens from endometrial samples of patients with a clinical diagnosis of postpartum endometritis. We then generated a list of the most common 20 genus and family ( Table 2).…”

A review of antibiotic therapy for pelvic inflammatory disease

“…Ceftriaxone plus doxycycline [39,40] 74.5% (91/122) 72-77% Ceftriaxone plus azithromycin [40] 90% (56/62) -Cefoxitin plus doxycycline [27][28][29][30][31][32][33][34] 83.9% (435/518) 62-97% Cefoxitin alone [35,36] 89.8% (44/49) 84-93% Doxycycline alone [37] 75% (18/24) -Doxycycline plus metronidazole [38] 70% (14/20) -Ofloxacin [33,34] 69.7% (115/165) 63-95% Ofloxacin plus metronidazole [41][42][43] 82.3% (726/882) 77.7-100% Clindamycin plus gentamicin [27,28,30,35,[43][44][45][46][47][48] 86.8% (363/418) 39-100% Clindamycin alone [49] 45% ( In the Ross et al study 18 (5.0%) of 363 patients treated with ofloxacin plus metronidazole withdrew from this regimen following the occurrence of side effects [42] and 10/578 (1.7%) in the Aş icioglu et al study [41].…”

“…Several studies have investigated the effectiveness of clindamycin plus gentamicin in the treatment of PID [27,28,30,35,[43][44][45][46][47][48], and the effectiveness of clindamycin alone was investigated in a single study [49]. Cure rates ranged from 39% to 100%.…”

Pelvic Inflammatory Disease

“…Different antibiotics compared with each other We don't know how different antibiotic regimens compare with each other at improving cure rates in women with confirmed pelvic inflammatory disease (PID) (very low-quality evidence). In review [19] See Further information on studies [24] RCT In review [19] See Further information on studies [25] RCT The review reported that overall trial quality was poor 52 In review [19] See Further information on studies [ [19] See Further information on studies [ [19] See Further information on studies [28] RCT The review reported that overall trial quality was poor 57 [19] See Further information on studies [ In review [19] See Further information on studies [30] RCT The review reported that overall trial quality was poor 80/128 (63%) with ofloxacin for full details of In review [19] See Further information on studies [ In review [19] See Further information on studies [32] RCT In review [19] See Further information on studies [33] RCT In review [19] See Further information on studies [34] RCT The review reported that overall trial quality was poor 10/10 (100%) with ciprofloxacin for full details of population included in review [19] See Further information on studies [35] RCT The review reported that overall trial quality was poor 33 In review [19] See Further information on studies [36] RCT The review reported that overall trial quality was poor 33/33 (100%) with ciprofloxacin (plus clindamycin in one women) for full details of population included in review In review [19] See Further information on studies [37] RCT The review reported that overall trial quality was poor 41/44 (93%) with meropenem for full details of population included in review In review [19] See Further information on studies [38] RCT The review reported...…”