Comparison of ocular biometric measurements in patients with cataract using three swept-source optical coherence tomography devices

Abstract

Background Precise measurement of ocular biometry is critical for determining intraocular lens power. Newly developed swept-source optical coherence tomography (SS-OCT) - based ocular biometric devices, ANTERION and CASIA2 provide ocular biometric measurements as IOLMaster 700. This study aimed to assess agreement between three devices. Methods This retrospective comparative study includes patients with cataract who underwent ocular biometric measurements with three devices, ANTERION, CASIA2, and IOLMaster 700, at Seoul National University Hospital, in April 2020. Anterior keratometry, total keratometry, central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT), and axial length (AL) were the main parameters for the comparison. To assess the agreement between the devices, intraclass coefficient (ICC) and Bland-Altman analysis with 95% limits of agreement (LoA) were used. Results A total of 47 eyes of 29 patients were measured with three devices. Average anterior keratometry showed excellent agreement (ICC ≥ 0.989), and the mean difference was less than 0.1 D. However, the ICC of the total average keratometry ranged from 0.808 to 0.952, and the difference was more than 0.43 D. The AL measured by ANTERION and IOLMaster 700 showed excellent agreement (ICC = 0.999), and the mean difference was 0.005 mm. The ANTERION and IOLMaster 700 did not obtain AL in six (12.8%) and three (6.4%) cases, respectively (P = 0.001 by Fisher’s exact test). The CCT, ACD, and LT also showed excellent agreement (ICC > 0.9). Conclusions The new SS-OCT-based devices, ANTERION, and CASIA2 showed a good agreement with IOLMaster 700 in measuring ocular biometry except for the total keratometry. The AL of ANTERION and IOLMaster 700 showed excellent agreement.

Evaluation of ocular biometry in primary angle-closure disease with two swept source optical coherence tomography devices

“…However, concordance between the devices was high, with differences that were not clinically relevant in IOL calculation. Oh et al [ 16 ] reported mean difference of AL 0.005 mm, with ICC 0.999 in their study of 47 eyes of 29 patients. CCT, ACD and keratometry revealed excellent agreement as well.…”

Agreement of Anterior Segment Parameter Measurements With CASIA 2 and IOLMaster 700

“…As we all know, if a new device wants to be recognized by clinicians and be widely used in clinical practice, it will be compared with the currently recognized instrument. As far as we know, there are currently few studies comparing CASIA 2 with IOLMaster 700 in anterior segment parameter measurements (16,17). The sample size of our study (81 eyes of 81 patients) is larger than the previous study comparing CASIA2 and IOLMaster 700 (48 eyes of 48 patients and 47 eyes of 29 patients, respectively).…”

Agreement of intraocular lens power calculation between 2 SS-OCT–based biometers

“…3 Oh et al reported excellent agreement for AL and anterior K but found no significant offset in ACD and LT in 29 patients. 7 Variations in ACD measurement contribute the most to errors in IOL power calculation, although substantial improvement has been achieved with modern biometers. 27 In accordance with previous findings, we measured a significantly deeper ACD with Biometer B for BUII, EVO 2.0, Haigis, Hoffer Q, Holladay 1, Kane, and SRK/T intraocular lens power calculation formulas.…”