Comparison of MTA versus Biodentine in Apexification Procedure for Nonvital Immature First Permanent Molars: A Randomized Clinical Trial

Abstract

This study aimed to evaluate the radiological and clinical outcomes of Biodentine apical plugs compared to mineral trioxide aggregate (MTA) in treating immature molars with apical lesions in children. Materials and Methods: Thirty immature roots of 24 permanent lower first molars with apical lesions were randomly divided into two groups: group 1 (15 roots) treated with MTA apical plugs and group 2 (15 roots) treated with Biodentine apical plugs. Treatment radiological outcomes were assessed using the periapical index (PAI) scale after 6 and 12 months of treatment. The presence or absence of apical calcified barrier (ACB) was assessed after 12 months of treatment. The visual analog scale (VAS) was used to compare the postoperative pain between the two groups after 1, 3, 7, and 14 days of treatment. PAI scores between the two groups were compared using the Mann–Whitney U test, the presence or absence of the ACB was compared using the chi-square test, and the VAS scores were compared using the t-test. The statistical significance threshold was set at 0.05. Results: There were no statistically significant differences in the PAI between the two groups at 6 and 12 months postoperatively. After 12 months, four cases in the Biodentine group showed ACB formation, whereas ACB was not found in any case treated with MTA. The VAS scores were statistically lower in the MTA group on the first day after treatment. Nevertheless, these scores were not statistically significantly different after 3, 7, and 14 days of treatment between the two groups. Conclusions: Biodentine can be used as an apical plug to treat immature permanent molars with apical lesions in a single visit in children. Biodentine showed favorable outcomes in apical lesions healing, which was comparable to MTA but with a decreased treatment time associated with its use.

Fracture Resistance of Molars With Simulated Strip Perforation Repaired With Different Calcium Silicate-Based Cements

“…According to the results of this study, no significant differences were observed among G1 (without SP), G3 (SP treated with MTA), and G4 (SP treated with bioceramic) (1083.73 N, 1025.20 N, and 1034.20 N, respectively), which meant that both MTA and bioceramic can similarly support and restore the correct structure of the tooth as if it was not affected by SP. Many laboratory and clinical studies have confirmed the role of MTA in supporting fragile dental structures and enhancing the survival of weakened teeth within the oral cavity during long follow-up periods, whether in treating immature teeth [ 25 ], perforations [ 21 ], or various absorptions [ 26 ]. Our current study corroborates this finding in SP treatment.…”

Can Diode Laser 810 decrease Post Endodontic Pain in Patients with Asymptomatic Necrotic Maxillary Incisors? A Four-Arm Randomized Controlled Trial

“…The PUI was adopted in the control group because this method is commonly and widely used as an IAS in laboratory, bacteriological, and clinical studies related to endodontics [45] [46] [47]. It was also mentioned that PUI can reduce the PP compared to conventional irrigation [48].…”

Management of Ellis Class-IV Fractured Tooth With an Open Apex: A Case Report

“…In this study, they concluded that biodentin can be used as an apical plug to treat immature permanent molars with periapical lesions. It also showed favorable outcomes in terms of healing of the periapical area, which was comparable with MTA, and also that biodentin has decreased treatment time [ 21 ]. Before using MTA, Torabinejad and Chivian advise using calcium hydroxide for the first week to control bleeding from the periapical region.…”