Comparison of Microwave Ablation and Multipolar Radiofrequency Ablation In Vivo Using Two Internally Cooled Probes

Fan, Weijun; Li, Xin; Zhang, Liang; Jiang, Hua; Zhang, Jianlei

doi:10.2214/ajr.11.6707

Cited by 77 publications

(43 citation statements)

References 17 publications

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“…Moreover, because MWA does not depend on the passage of electricity through tissues as RFA does, multiple applicators can be used simultaneously to create larger ablation zones and shorten the procedural time. Faster ablation times, larger ablation zones, and higher intratumoral temperatures have been observed with MWA in ex vivo bovine [58,59] and in vivo porcine [60] animal models. Given its increased efficacy in ablation and shorter time to achieve ablations, MWA has increasingly been used in treating HCC [61,62,63,64,65,66,67].…”

Section: Local Ablative Therapymentioning

confidence: 99%

A Recent Advance in Image-Guided Locoregional Therapy for Hepatocellular Carcinoma

Shi

Zhai

2016

Gastrointest Tumors

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Background: Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide and the third most common cause of cancer-related deaths. Hepatic resection and liver transplantation are considered to be the preferred treatment for HCC. However, as novel therapeutic options such as image-guided locoregional therapies have emerged and been refined, the manner in which HCC is treated has changed dramatically compared with what it was considered just 2 decades earlier. Summary: This study reviews the current results of various image-guided locoregional therapies for treating HCC, especially focusing on thermal ablative and transarterial techniques. Key Message: Advances in image-guided locoregional therapies, including local ablative therapy and transarterial therapy, have led to a major breakthrough in the management of HCC. Both survival rates and cure rates of patients with HCC have improved markedly since the introduction of these techniques. Practical Implications: Radiofrequency ablation is currently considered as an alternative to surgical resection for patients with early-stage HCC. A newer technique of ablation such as microwave ablation is increasingly being used, especially for large HCC. Transarterial chemoembolization has become a standard care for asymptomatic patients with multinodular tumors in intermediate-stage disease, and transarterial radioembolization has become the method of choice in HCC cases with portal vein thrombosis. Moreover, combination treatment modalities, such as thermal-based ablation combined with transarterial chemoembolization or ¹²⁵I seed implant brachytherapy, may further broaden their clinical indications for HCC. Moreover, use of localized radiation in combination with thermal ablation has been reported to improve tumor control and long-term survival.

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Section: Local Ablative Therapymentioning

confidence: 99%

A Recent Advance in Image-Guided Locoregional Therapy for Hepatocellular Carcinoma

Shi

Zhai

2016

Gastrointest Tumors

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“…Microwave ablation (MWA) is also utilised to generate thermal ablation. New devices have a greater burn area with a more consistent penumbra when compared to RFA [95,96]. These treatments are likely to have an evolving role in the future either in combination with resection or in isolation [97].…”

Section: Operative Approachmentioning

confidence: 99%

Surgery for Colorectal Liver Metastases

McNally

Parks²

2013

Dig Surg

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Half of all patients with colorectal cancer develop metastatic disease. The liver is the principal site for metastases, and surgical resection is the only modality that offers the potential for long-term cure. Appropriate patient selection for surgery and improvements in perioperative care have resulted in low morbidity and mortality rates, resulting in this being the therapy of choice for suitable patients. Modern management of colorectal liver metastases is multimodal incorporating open and laparoscopic surgery, ablative therapies such as radiofrequency ablation or microwave ablation and (neo)adjuvant chemotherapy. The majority of patients with hepatic metastases should be considered for resectional surgery, if all disease can be resected, as this offers the only opportunity for prolonged survival.

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“…After having overcome initial technical problems such as power loss at the cable and critical heating of the antenna shaft, microwave (MW) ablation has developed into an alternative to RF ablation with several advantages [7]. In contrast to RF ablation, MW ablation is independent of the impedance of the surrounding tissue and can thus generate higher temperatures, leading to larger ablation zones in a shorter time [8][9][10]. Furthermore, MW ablation is less susceptible to the heat-sink effect caused by vessels in the target lesion, which is thought to be a reason for local tumour recurrence [11,12].…”

Section: Introductionmentioning

confidence: 99%

“…Furthermore, MW ablation is less susceptible to the heat-sink effect caused by vessels in the target lesion, which is thought to be a reason for local tumour recurrence [11,12]. Another advantage is the more circular ablation zone produced by MW ablation, which is of particular importance in the treatment of larger tumours [8,13].…”

Section: Introductionmentioning

confidence: 99%

In vitro artefact assessment of a new MR-compatible microwave antenna and a standard MR-compatible radiofrequency ablation electrode for tumour ablation

et al. 2015

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Comparison of Microwave Ablation and Multipolar Radiofrequency Ablation In Vivo Using Two Internally Cooled Probes

Abstract: MWA, by the simultaneous application of double antennae, can generate a larger ablation zone, in vivo, compared with multipolar RFA.

Cited by 77 publications

References 17 publications

A Recent Advance in Image-Guided Locoregional Therapy for Hepatocellular Carcinoma

A Recent Advance in Image-Guided Locoregional Therapy for Hepatocellular Carcinoma

Surgery for Colorectal Liver Metastases

In vitro artefact assessment of a new MR-compatible microwave antenna and a standard MR-compatible radiofrequency ablation electrode for tumour ablation

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