Comparison of Marketed Cosmetic Products Constituents with the Antigens Included in Cosmetic-related Patch Test

Cheong, Seung Hyun; Choi, You Won; Myung, Ki Bum; Choi, Hae Young

doi:10.5021/ad.2010.22.3.262

Cited by 3 publications

(2 citation statements)

References 39 publications

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“…A study in Seoul found that not all antigens that are found in cosmetics are actually available in patch test kits and that these could be potential allergens which go undetected; hence, a need for regular modification of testing kits to reflect ingredients in the cosmetics is advocated [ 15 ]. In India, a study on pediatric contact dermatitis revealed that children could be sensitive to some of the cosmetic antigens and the sensitization may happen due to early age of cosmetic use [ 16 ].…”

Section: Discussionmentioning

confidence: 99%

Patch Testing in Suspected Allergic Contact Dermatitis to Cosmetics

Kumar

Paulose

2014

Dermatology Research and Practice

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Background. Increasing use of cosmetics has contributed to a rise in the incidence of allergic contact dermatitis (ACD) to cosmetics. It is estimated that 1–5.4% of the population is sensitized to a cosmetic ingredient. Patch testing helps to confirm the presence of an allergy and to identify the actual allergens which are chemical mixtures of various ingredients. Objectives. The aims of this study are to perform patch testing in suspected ACD to cosmetics and to identify the most common allergen and cosmetic product causing dermatitis. Methods. Fifty patients with suspected ACD to cosmetics were patch-tested with 38 antigens of the Indian Cosmetic Series and 12 antigens of the Indian Standard Series. Results. The majority (58%) of patients belonged to the 21–40 years age group. The presence of ACD to cosmetics was confirmed in 38 (76%) patients. Face creams (20%), hair dyes (14%), and soaps (12%) were the most commonly implicated. The most common allergens identified were gallate mix (40%), cetrimide (28%), and thiomersal (20%). Out of a total of 2531 patches applied, positive reactions were obtained in 3.75%. Conclusion. Incidence of ACD to cosmetics was greater in females. Face creams and hair dyes were the most common cosmetic products implicated. The principal allergens were gallate mix, cetrimide, and thiomersal.

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Section: Discussionmentioning

confidence: 99%

Patch Testing in Suspected Allergic Contact Dermatitis to Cosmetics

Kumar

Paulose

2014

Dermatology Research and Practice

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“…The most common causes of ACD are minerals such as nickel, chromium, cobalt, gold and organic chemicals [3]. In Korea, lacquer [4], rubber [5], hair dye [6], minerals (such as nickel, chromium, cobalt, and mercury), and cosmetics [7] are the main causes of ACD. Those chemicals work as haptens, which induce an immune response only when attached to larger molecules.…”

Section: Introductionmentioning

confidence: 99%

Allergic contact dermatitis of both eyes caused by alcaftadine 0.25%: a case report

Kim

2019

BMC Ophthalmol

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Background To report the first case of allergic contact dermatitis (ACD) associated with alcaftadine 0.25% ophthalmic solution. Case presentation The patient was a 51-year-old woman with no previous history of side effects to ophthalmic antihistamine agents. She had been prescribed alcaftadine 0.25% for allergic conjunctivitis. On first application of the medication, she did not experience any cutaneous reaction. One day later, after the second alcaftadine 0.25% application, both eyelids became swollen, and erythematous changes were evident. On slit-lamp examination, conjunctival injection was noted in the absence of conjunctival swelling or any other findings. Fundus examination was unremarkable. To evaluate the cause of ACD, a patch test was performed and 48 h later was noted to be positive for alcaftadine 0.25%. Based on the positive patch test, the patient was diagnosed with ACD caused by alcaftadine 0.25%. After 9 days of treatment, the swelling and erythema completely resolved. Conclusions Although there have been no previous reports of alcaftadine 0.25%-associated ACD, it should be suspected in patients with swelling and erythematous change of both eyes after using alcaftadine 0.25%.

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A Review of Moisturizers; History, Preparation, Characterization and Applications

et al. 2022

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Moisturizers are one of the most widely used preparations in cosmetics and have been extensively used to soften the skin for consumers. Moisturizers work effectively in combating dry skin which may cause pain, tightness, itch, stinging, and/or tingling. The aim of this review is to evaluate published studies on the history, ingredients, preparation processes, characteristics, uses, and applications of moisturizers. Moisturizers bridge the gap between medicine and consumer goods by being used to make the skin more beautiful and healthy. In the future, in moisturizer therapy, the capacity to adapt specific agents to specific dermatological demands will be crucial. Cosmetically, moisturizers make the skin smooth by the mechanism of increasing the water content in the stratum corneum, hence exerting its most vital action, which is moisturizing action and maintaining a normal skin pH.

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Comparison of Marketed Cosmetic Products Constituents with the Antigens Included in Cosmetic-related Patch Test

Cited by 3 publications

References 39 publications

Patch Testing in Suspected Allergic Contact Dermatitis to Cosmetics

Patch Testing in Suspected Allergic Contact Dermatitis to Cosmetics

Allergic contact dermatitis of both eyes caused by alcaftadine 0.25%: a case report

A Review of Moisturizers; History, Preparation, Characterization and Applications

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