Comparison of Long-Term Prognostic Evaluation Between Pre-Intervention Thrombolysis and Primary Coronary Intervention: A Prospective Randomized Trial  - Five-Year Results of the IMPORTANT Study -

Itoh, Tomonori; Fukami, Kenichi; Suzuki, Tomomi; Kimura, Takeshi; Kanaya, Yoshinori; Orii, Makoto; Goto, Iwao; Matsui, Hiroki; Sugawara, Shoma; Nakajima, Shigeru; Fusazaki, Tetsuya; Nakamura, Motoyuki; Investigators, I Smart-Pd

doi:10.1253/circj.cj-09-0873

Cited by 17 publications

(7 citation statements)

References 25 publications

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Section: Discussionsupporting

confidence: 90%

“…In that study, mean EF values of patients who received thrombolytic therapy were 55.4% at the time of admission and 61.6% after six months; mean EF of patients who underwent PCI was 54.3% at the time of admission and 55% after six months of follow up. The Itho study results are in line with this study, and both of them demonstrate that EF raised signi cantly during a long time after thrombolytic therapy[34].ConclusionHistory of hypertension and diabetes are the most critical risk factors for occurring STEMI in smoker patients. This study showed that only 7.1% of patients with MI are admitted to the hospital within the golden time of 30 minutes.…”

supporting

confidence: 88%

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The Outcome of Smoker Patients With ST-Elevation Myocardial Infarction (STEMI) Undergone Primary Percutaneous Coronary Intervention (P-PCI) Versus Thrombolytic Therapy

Karimi

Piranfar

Fesharaki

et al. 2021

Preprint

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Background: Because of the high prevalence of cardiovascular diseases and their urgent treatment in a way that have minimal side effects and maximum benefits, this study aims to compare the mortality rate, re-hospitalization, and ejection fraction of smoker patients undergone P-PCI (primary percutaneous coronary intervention) with those who received thrombolytic therapy in autumn 2018.Methods: This cross-sectional study was done in Ayatollah Taleghani and Labbafinejad hospitals of Tehran City, Iran. The study group consisted of 42 smoker patients referred to the hospitals with the diagnosis of ST-Elevation Myocardial Infarction (STEMI) and have undergone P-PCI or thrombolytic therapy from September 2018 to December 2018. Complications such as death and re-hospitalization were noted, and the ejection fraction of each patient was also recorded. Statistical analyses were performed using SPSS version 25. Statistical significance was considered at P< 0.05.Results: The Independent Samples t-test showed no significant difference between two groups of PCI and thrombolytic therapy regarding ejection fraction (EF) at the time of admission. Also, there was no considerable EF difference after three months of follow-up between 2 groups in both smoker and ex-smoker ones (P>0.05). Mean (SD) values of EF in smoker patients who underwent PCI were 41.56 9.95 at the time of admission and 45.00 10.52 after three months of follow-up. The paired sample t-test showed no significant difference between both groups regarding EF at the time of admission and after three months. The mean (SD) values of EF in smoker patients who underwent thrombolytic therapy were 40.26 8.73 at the time of admission and 48.53 5.80 after three months of follow-up. The paired sample t-test showed no significant difference between EF at the time of admission and after three months in the ex-smoker group, but there was a considerable difference in the smoker group (P<0.05). Three months mortality rate was estimated at 23.1% in smokers with PCI and 7.1% in patients treated with thrombolytic therapy. Conclusion: Thrombolytic therapy can increase the EF of smoking patients with STEMI for a long time, indicating a beneficial effect of thrombolytic therapy to prevent heart failure.

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Section: Discussionsupporting

confidence: 90%

supporting

confidence: 88%

The Outcome of Smoker Patients With ST-Elevation Myocardial Infarction (STEMI) Undergone Primary Percutaneous Coronary Intervention (P-PCI) Versus Thrombolytic Therapy

Karimi

Piranfar

Fesharaki

et al. 2021

Preprint

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“…To understand the real value of the new proposed risk model, prospective multicenter validation is necessary. Third, front-line LM-ACS lesion management changed over the study period, from thrombolytic therapy to stent or thrombus aspiration catheter, [29][30][31][32] and we did not evaluate prognostic differences resulting from each reperfusion therapy. Finally, although the GRACE risk score can be used at the time of admission to the emergency room, before angiography, the LM risk score can only be used after angiography.…”

Section: Study Limitationsmentioning

confidence: 99%

Electrocardiographic characteristics associated with in-hospital outcome in patients with left main acute coronary syndrome: For contriving a new risk stratification score

Iida

Tanimura

Takahashi

et al. 2016

European Heart Journal: Acute Cardiovascular Care

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“…Ova strategija identična je i za pacijenata sa STEMI bez srčanog zastoja. 155,156,157 • Kod komatoznih pacijenata sa ROSC koji su doživeli vanbolnički srčani zastoj kada postoji sumnja na srčano poreklo zastoja bez ST-elevacije na EKG-u, potrebno je razmotriti hitnu kateterizaciju. 158…”

Section: Dijagnostičke Procedures Kod Aksunclassified

Preporuke 2015 - Međunarodni naučni konsenzus o kardiopulmonalnoj reanimaciji

Raffay¹,

Fiser²,

Tijanic³

et al. 2016

J Resuscitatio Balcan

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(RCA). Od 2000. godine istraživači ILCOR ocenjuju resuscitacionu nauku u petogodišnjim ciklusima. Najnoviji međunarodni konsenzus, konferencija održana je u Dallasu u februaru 2015. godine i objavljeni zaključci i preporuke iz ovog saopštenja čine osnovu ovih Preporuka ERC 2015. Osim šest ILCOR radnih grupa: osnovna životna podrška (BLS); napredna podrška života (ALS); akutni koronarni sindromi (ACS); pedijatrijska podrška života (PLS); neonatalna podrška života (NLS) edukacija, implementacija i trening (EIT); iz 2010. godine, formirana je i Radna grupa za prvu pomoć. Kao i 2010. godine pripremljen je dokument o konfliktu interesa. Za svaku temu su pozvana najmanje dva stručna recezenta da daju nezavisne procene. Njihov rad je podržan od strane novog i jedinstvenog online sistema SEERS (Scientific Evidence Evaluation and Review System), koji je razvijen od strane ILCOR. Za procenu kvaliteta dokaza i snage preporuka, ILCOR je usvojio metodologiju GRADE (ocenjivanje preporuka, procena, razvoj i evaluacija). Na ILCOR 2015 konsenzus konferenciji je učestvovalo 232 učesnika koji predstavljaju 39 zemalja; 64% učesnika je došao van SAD. To učestvovanje je obezbedilo da ova konačna objava preporuka predstavlja stvarni međunarodni konsenzus proces. Tokom tri godine pre konferencije, 250 dokaza su pregledali recenzenti iz 39 zemalja, hiljadu relevantnih, publikacija na temu169 specifičnih pitanja, svaki u standardnom PICO formatu (stanovništvo, intervencija, upoređivanje, ishod). Svaka naučna izjava sadrži ekspertsku interpretaciju svih relevantnih podataka na određenu temu i relevantna ILCOR radna grupa dodaje konsenzus nacrta tretmana za preporuku. Konačni tekst naučnih izjava i preporuka za lečenje je završen nakon daljnjeg pregleda od strane organizacije ILCOR članova i uredništva i publikovan u Resuscitation i Circulation kao Naučni konsenzus 2015. preporučenih postupaka (Consensus on Science and Treatment Recommendations-CoSTR). Organizacija članova koju čini ILCOR će objaviti prepouke koje su u skladu s ovim CoSTR dokumentom, ali će takođe razmotriti geografske, ekonomske i sistemske razlike u praksi, dostupnost medicinskim proizvodima i lekovima.

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Comparison of Long-Term Prognostic Evaluation Between Pre-Intervention Thrombolysis and Primary Coronary Intervention: A Prospective Randomized Trial - Five-Year Results of the IMPORTANT Study -

Cited by 17 publications

References 25 publications

The Outcome of Smoker Patients With ST-Elevation Myocardial Infarction (STEMI) Undergone Primary Percutaneous Coronary Intervention (P-PCI) Versus Thrombolytic Therapy

The Outcome of Smoker Patients With ST-Elevation Myocardial Infarction (STEMI) Undergone Primary Percutaneous Coronary Intervention (P-PCI) Versus Thrombolytic Therapy

Electrocardiographic characteristics associated with in-hospital outcome in patients with left main acute coronary syndrome: For contriving a new risk stratification score

Preporuke 2015 - Međunarodni naučni konsenzus o kardiopulmonalnoj reanimaciji

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