Comparison of lobectomy and wedge resection for carcinoma of the lung

Treatment of Stage I and II Non-Small-Cell Lung Cancer

“…Multiple retrospective studies between 1979-1990 addressed this question, although results were not conclusive. In a comparison of these two groups, Hoffmann et al 11 found no difference in survival at 1, 2, and 5 years, although a 5-year survival rate of 25% in the lobectomy group for early-stage NSCLC reported in this study is low. Errett et al 12 also reported a similar 5-year survival rate in stage I patients treated with lobectomy (n=97, 75%) and wedge resection (n=100, 69%) at 6 years.…”

Relationship between margin distance and local recurrence among patients undergoing wedge resection for small (≤2 cm) non–small cell lung cancer

“…In the published data, the local recurrence rate for wedge resection has varied from 2.7% to 30.0% for NSCLC stage I. [2][3][4][5][6][7] What is unknown is the safe limit of a wedge resection margin distance for a small size lung cancer and how the technique of wedge resection affects the extent of this margin and the ability to perform facile, prompt, and accurate pathologic assessments. Furthermore, in the published data, no clear guidelines are available regarding the margin distance for small tumors.…”

“…1 Currently, complete surgical resection is the ideal treatment modality for patients with early-stage non-small cell lung cancer (NSCLC). Among the different surgical options, wedge resection has been the most common limited resection technique used to remove NSCLC, [2][3][4][5][6] although lobectomy and lymph node dissection are currently the standard treatment for small peripheral resectable NSCLC. 7 Similarly, many studies on the changing histopathologic patterns of lung cancer have been reported.…”

Meta‐analysis of lobectomy, segmentectomy, and wedge resection for stage I non‐small cell lung cancer

“…There were 37 studies included for the OS/CSS analysis of sublobectomy versus lobectomy in stage I NSCLC [1,2,[6][7][8]11,[15][16][17][18][19][20][22][23][24][25][26][27][28][29][30][31][33][34][35][36][37][38][39][40][41][42][43][44][45][46][47]. Random-effect model was used due to the significant heterogeneity (P < 0.001).…”