Meta‐analysis of lobectomy, segmentectomy, and wedge resection for stage I non‐small cell lung cancer

Zhang, Yang; Sun, Yihua; Wang, Rui; Ye, Ting; Zhang, Yiliang; Chen, Haiquan

doi:10.1002/jso.23800

Cited by 89 publications

(73 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Mortality was also higher in the limited resection group, but did not reach statistical significance (7,8). The study is more than 20 years old, but a recent meta-analysis has confirmed that lobectomy is still better than limited resection for stage IA ≤2 cm tumours (9). This also has been observed in a recent population-based study comprising 15,760 patients with T1aN0M0 non-small cell lung cancers (10,493 or 66% adenocarcinomas) from the Surveillance, Epidemiology and End Results database who underwent lobectomy, segmentectomy or wedge resection.…”

mentioning

confidence: 80%

Tiny lung adenocarcinomas: better prognosis with a word of caution

Rami‐Porta

2016

J. Thorac. Dis.

View full text Add to dashboard Cite

mentioning

confidence: 80%

Tiny lung adenocarcinomas: better prognosis with a word of caution

Rami‐Porta

2016

J. Thorac. Dis.

View full text Add to dashboard Cite

“…In individuals with severe disease and resectable lung cancer, there is evidence that newer surgical treatments (sublobar resection or lung volume reduction surgery [LVRS]) and ablative therapies (stereotactic radiosurgery or radiofrequency ablation) are valid alternatives to consider due to their acceptable risk and good long-term outcomes [48][49][50][51][52][53] . There are even reports of successful lung cancer surgical treatments in patients that previously underwent endobronchial LVRS for severe emphysema 54 .…”

Section: Clinical Considerationsmentioning

confidence: 99%

Use of Biomarkers in Chronic Obstructive Pulmonary Disease: Clinical Implications

Moon¹,

Cho²,

Sin³

2018

BRN

View full text Add to dashboard Cite

“…For tumors less than 2 cm, segmentectomy was equivalent to lobectomy. Recently, Zhang et al [20] reported a meta-analysis of sublobectomy (segmentectomy and wedge resection) vs. lobectomy. They selected 53 studies from the PubMed and EMBASE databases and showed that the indication for sublobar resection due to tumor size (less than 2 cm) or age alone would not be sufficient.…”

Section: Meta-analysismentioning

confidence: 99%

Therapeutic strategy for small-sized lung cancer

Iwata

2016

Gen Thorac Cardiovasc Surg

View full text Add to dashboard Cite

Minimizing the volume of lung resection without diminishing curability has recently become an important issue in primary lung cancer. In this review, we will discuss the current state of the feasibility of sublobar resection and specific issues for a segmentectomy procedure. A previous randomized controlled trial showed that lobectomy must still be considered the standard surgical procedure compared with sublobar resection for T1N0 non-small cell lung cancer with a tumor less than 3 cm in size. Since then, supporting studies for segmentectomy of lung cancer with a tumor less than 2 cm in size were reported. In addition, segmentectomy seems to be feasible for clinical stage I adenocarcinoma less than 2 cm in size, in women younger than 70 years old, with a low tumor 18F-fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET) standardized uptake value (SUV) from propensity-matching studies. In a meta-analysis of sublobar resection vs. lobectomy, intentionally performed sublobar resection showed equivalent outcomes to lobectomy. In the near future, two ongoing prospective, randomized trials will report results. As specific issues for the surgical procedure of segmentectomy, achieving a sufficient surgical margin is an important issue for preventing loco-regional recurrence. More studies regarding the regional lymph node dissection area for segmentectomy are needed. Sublobar resection has the potential to become the standard procedure for peripheral small-sized lung cancer less than 2 cm. However, more information is needed about the characteristics of this cancer and the surgical procedure, including nodal dissection.

show abstract

Meta‐analysis of lobectomy, segmentectomy, and wedge resection for stage I non‐small cell lung cancer

Cited by 89 publications

References 46 publications

Tiny lung adenocarcinomas: better prognosis with a word of caution

Tiny lung adenocarcinomas: better prognosis with a word of caution

Use of Biomarkers in Chronic Obstructive Pulmonary Disease: Clinical Implications

Therapeutic strategy for small-sized lung cancer

Contact Info

Product

Resources

About