Comparison of intravenous ibuprofen and acetaminophen for postoperative multimodal pain management in bariatric surgery: A randomized controlled trial

Kayhan, Gülay Erdoğan; Şanlı, Mukadder; Özgül, Ülkü; Kırteke, Ramazan; Yoloğlu, Saim

doi:10.1016/j.jclinane.2018.06.030

Cited by 33 publications

(48 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Non-opioid pharmacological (e.g., acetaminophen and nonsteroidal anti-inflammatory drugs) and non-pharmacological treatments (e.g., physical therapy, chiropractic, acupuncture, relaxation techniques, etc.) are not only shown to be associated with lower rates of opioid prescription and misuse [ 36 , 37 , 38 , 39 ], but reported to be as effective as opioids in managing pain conditions, especially chronic conditions [ 40 , 41 , 42 ]. As another medium, cannabis use or legalizing it in many U.S. states has been shown to be associated with lower rates of opioid prescriptions [ 43 , 44 , 45 , 46 ].…”

Section: Resultsmentioning

confidence: 99%

Misalignment of Stakeholder Incentives in the Opioid Crisis

Boloori

Arnetz

Viens

et al. 2020

IJERPH

View full text Add to dashboard Cite

The current opioid epidemic has killed more than 446,000 Americans over the past two decades. Despite the magnitude of the crisis, little is known to what degree the misalignment of incentives among stakeholders due to competing interests has contributed to the current situation. In this study, we explore evidence in the literature for the working hypothesis that misalignment rooted in the cost, quality, or access to care can be a significant contributor to the opioid epidemic. The review identified several problems that can contribute to incentive misalignment by compromising the triple aims (cost, quality, and access) in this epidemic. Some of these issues include the inefficacy of conventional payment mechanisms in providing incentives for providers, practice guidelines in pain management that are not easily implementable across different medical specialties, barriers in adopting multi-modal pain management strategies, low capacity of providers/treatments to address opioid/substance use disorders, the complexity of addressing the co-occurrence of chronic pain and opioid use disorders, and patients’ non-adherence to opioid substitution treatments. In discussing these issues, we also shed light on factors that can facilitate the alignment of incentives among stakeholders to effectively address the current crisis.

show abstract

Section: Resultsmentioning

confidence: 99%

Misalignment of Stakeholder Incentives in the Opioid Crisis

Boloori

Arnetz

Viens

et al. 2020

IJERPH

View full text Add to dashboard Cite

show abstract

“…Ciftci et al, 2019 found that an ibuprofen 800 mg group showed low pain scores and minor rescue analgesic intake when compared to the acetaminophen 1000 mg group after laparoscopic sleeve gastrectomy [42]. Erdogan-Kayhan et al, 2018, reported that ibuprofen 400 mg reduced the pain intensity scores in comparison to acetaminophen 1000 mg in bariatric surgery [43].…”

Section: Discussionmentioning

confidence: 99%

A Meta-Analysis of the Analgesic Efficacy of Single-Doses of Ibuprofen Compared to Traditional Non-Opioid Analgesics Following Third Molar Surgery

et al. 2021

View full text Add to dashboard Cite

The purpose of this systematic review was to determine the analgesic efficacy and adverse effects of ibuprofen in comparison with other traditional non-opioid analgesics after third molar surgery. A total of 17 full texts were identified in PubMed and assessed using the Cochrane Collaboration’s risk of bias tool by two independent researchers. The sum of pain intensity differences, total pain relief, the overall evaluation, the number of patients requiring rescue analgesics, and adverse effects were collected. Data were analyzed using the Review Manager Software 5.3. for Windows. A total of 15 articles met the criteria. The qualitative and quantitative analysis showed that ibuprofen is more effective to relieve post-operative dental pain than acetaminophen, meclofenamate, aceclofenac, bromfenac, and aspirin. Moreover, ibuprofen and traditional non-steroidal anti-inflammatory drugs have a similar safety profile. In conclusion, ibuprofen 400 mg appears to have good analgesic efficacy and a safety profile similar to other traditional non-steroidal anti-inflammatory drugs after third molar surgery.

show abstract

“…Yalçınlı et al stated that intravenous ibuprofen is more effective than paracetamol in soft tissue injuries in patients admitted to emergency department [12] . On the other hand, Erdogan Kayhan et al showed that intravenous ibuprofen did not change the opioid consumption compared to paracetamol, but it reduced the severity of pain in patients who had bariatric surgery [13] . Çelik et al stated that ibuprofen was more effective in the first 12 hours in patients who underwent septorhinoplasty, but there was no difference between the two agents afterwards [14] .…”

Section: Discussionmentioning

confidence: 99%

Karotis Arter Stenozunda Cerrahi Endarterektomi ile Endovasküler Stent İmplantasyonunun Orta ve Geç Dönemde Morbidite ve Mortalite Sonuçlarının Karşılaştırılması

Bermede¹,

Baytaş²

2021

GKDA Derg

View full text Add to dashboard Cite

Objectives: The aim of this study is to compare the effects of preemptive intravenous ibuprofen and paracetamol on acute pain scores, opioid consumption and patient satisfaction in patients who will undergo endovascular laser ablation under general anesthesia. Methods: After induction, 1 g Paracetamol for Group P or 800 mg Ibuprofen for Group I was administered as a slow infusion by a separate intravenous route. Both drugs were followed by a repeat dose every 6 h until discharge. Visual analogue scale (VAS) was used for pain intensity at PACU and after the first, second, sixth hour after surgery. In case of acute pain (VAS ≥ 40) 1 mg intravenous morphine was used as a rescue drug. VAS scores, length of stay, total opioid consumption and patient satisfaction status was evaluated before discharge. Results: A total of 82 patients (42 in Group P and 40 in Group I) were included. There was no difference between the VAS scores. Total morphine consumption was 0.33 ± 0.47 in Group P, and 0.30 ± 0.43 in Group I (p = 0.42). Hospital length of stay was 6.4 ± 1.7 hours in Group P and 6.2 ± 1.4 hours in Group I (p = 0.51). Patient satisfaction status evaluated at discharge was found to be similar. Conclusion: There is no difference between preemptive intravenous paracetamol and ibuprofen in patients undergoing EVLA under general anesthesia in terms of postoperative acute pain scores and opioid consumption. Both drugs can be safely applied in this type of surgery.

show abstract

Comparison of intravenous ibuprofen and acetaminophen for postoperative multimodal pain management in bariatric surgery: A randomized controlled trial

Cited by 33 publications

References 27 publications

Misalignment of Stakeholder Incentives in the Opioid Crisis

Misalignment of Stakeholder Incentives in the Opioid Crisis

A Meta-Analysis of the Analgesic Efficacy of Single-Doses of Ibuprofen Compared to Traditional Non-Opioid Analgesics Following Third Molar Surgery

Karotis Arter Stenozunda Cerrahi Endarterektomi ile Endovasküler Stent İmplantasyonunun Orta ve Geç Dönemde Morbidite ve Mortalite Sonuçlarının Karşılaştırılması

Contact Info

Product

Resources

About