Karotis Arter Stenozunda Cerrahi Endarterektomi ile Endovasküler Stent İmplantasyonunun Orta ve Geç Dönemde Morbidite ve Mortalite Sonuçlarının Karşılaştırılması

Abstract

Objectives: The aim of this study is to compare the effects of preemptive intravenous ibuprofen and paracetamol on acute pain scores, opioid consumption and patient satisfaction in patients who will undergo endovascular laser ablation under general anesthesia. Methods: After induction, 1 g Paracetamol for Group P or 800 mg Ibuprofen for Group I was administered as a slow infusion by a separate intravenous route. Both drugs were followed by a repeat dose every 6 h until discharge. Visual analogue scale (VAS) was used for pain intensity at PACU and after the first, second, sixth hour after surgery. In case of acute pain (VAS ≥ 40) 1 mg intravenous morphine was used as a rescue drug. VAS scores, length of stay, total opioid consumption and patient satisfaction status was evaluated before discharge. Results: A total of 82 patients (42 in Group P and 40 in Group I) were included. There was no difference between the VAS scores. Total morphine consumption was 0.33 ± 0.47 in Group P, and 0.30 ± 0.43 in Group I (p = 0.42). Hospital length of stay was 6.4 ± 1.7 hours in Group P and 6.2 ± 1.4 hours in Group I (p = 0.51). Patient satisfaction status evaluated at discharge was found to be similar. Conclusion: There is no difference between preemptive intravenous paracetamol and ibuprofen in patients undergoing EVLA under general anesthesia in terms of postoperative acute pain scores and opioid consumption. Both drugs can be safely applied in this type of surgery.