Comparison of intravenous colloid and colloid-crystalloid combination in hypotension prophylaxis during spinal anesthesia for cesarean section

Idehen, HO; Amadasun, FE; Ekwere, IT

doi:10.4103/1119-3077.130231

Cited by 8 publications

(6 citation statements)

References 14 publications

(15 reference statements)

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“…Intravertebral anesthesia can effectively decrease the peripheral vascular resistance (PVR) and reduce returned blood volume, thus lowering the myocardial oxygen consumption; during the anesthesia process, trachea intubation is not needed, so that the interference of mechanical ventilation in blood circulation can be avoided, and the risk of pulmonary infection is reduced. General anesthesia decreases the occurrence of acute pulmonary edema in the patients through the analgesia, sedation and muscle relaxation effects; the application of ventilator support improves the oxygen supply to the patients, but it increases the risk of pulmonary infection at the same time; drugs have different degrees of inhibition on the patients' cardiac functions ( 10 , 11 ).…”

Section: Discussionmentioning

confidence: 99%

Association of hemodynamics during caesarean section, outcomes after caesarean section and hormone changes with different anesthesia in pregnant women with severe pulmonary arterial hypertension

Wang

et al. 2018

Exp Ther Med

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In the present study we aimed to analyze the effects of different anesthesia methods on the hemodynamics of caesarean section, outcomes after caesarean section and hormone changes in pregnancy complicated with severe pulmonary arterial hypertension (PAH). A total of 75 pregnancy complicated with severe PAH that were treated in Jining First People's Hospital from January 2016 to January 2017 were selected. Three groups were set according to the anesthesia methods, including the subarachnoid combined epidural anesthesia group (group I, n=25), the epidural anesthesia group (group II, n=25) and the general anesthesia group (group III, n=25). Effects on the outcomes of caesarean section of pregnancy complicated with PAH were observed. Sex hormone levels before and 24, 48 and 72 h after the operation were measured. There were remarkable changes in the postoperative hemodynamics compared with those before anesthesia, but changes in groups I and II were significantly smaller than those in group III (P<0.05). No significant differences in maternal mortality rate, neonatal mortality rate and neonatal asphyxia rate among the three groups were found (P>0.05). Time of postoperative mechanical ventilation, ICU residence and hospitalization in groups I and II were shorter than those in group III, the differences were statistically significant (P<0.05). Postoperative levels of sex hormones, including estradiol (E2), human chorionic gonadotrophin (HCG), prolactin (PRL) and plasma total testosterone (TT) decreased, while postoperative levels of sex hormones follicle stimulating hormone (FSH), luteinizing hormone (LH) and progestogen increased, and differences in the decreased E2 and TT at each time-point were statistically significant (P<0.05). In conclusion, there is no remarkable difference in the effects of three anesthesia methods on pregnancy outcomes. However, compared with general anesthesia, intravertebral anesthesia achieve shorter time of postoperative mechanical ventilation, ICU residence and hospitalization in pregnancy complicated with severe PAH, which is preferred in pregnancy without contraindication of the anesthesia.

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Section: Discussionmentioning

confidence: 99%

Association of hemodynamics during caesarean section, outcomes after caesarean section and hormone changes with different anesthesia in pregnant women with severe pulmonary arterial hypertension

Wang

et al. 2018

Exp Ther Med

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“…Beyond 10 min, the combination had no advantage. [ 14 ] In another study, crystalloid prehydration seems to be of little use and current focus is on timing of administration of fluids and use of colloids. It was proved that phenylephrine was proved to be as good as ephedrine for maintaining BP and a more liberal use of this drug were justified.…”

Section: Discussionmentioning

confidence: 99%

Six percent hetastarch versus lactated Ringer's solution – for preloading before spinal anesthesia for cesarean section

2016

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Background:Regional anesthesia has been the choice of preference for elective cesarean sections. This study was designed to determine whether preoperative administration of 6% hetastarch decreases the incidence of hypotension.Materials and Methods:This study was conducted on 50 nonlaboring American Society of Anesthesiologists class I and II women undergoing elective cesarean section. Patients were randomly divided into two groups and were preloaded either with 1000 ml Ringer's lactate (RL) or 500 ml of 6% hetastarch 30 min prior to the surgery. Spinal anesthesia was performed with patients in the left lateral position and 2 cc (10 mg) of 0.5% of bupivacaine injected into subarachnoid space. Hemodynamic variables (heart rate, noninvasive blood pressure, and SpO2) were recorded from prior to preloading until the recovery from the subarachnoid blockade.Results:Our study showed the incidence of hypotension to be 28% in the hetastarch group and 80% in the RL group. Rescue ephedrine requirements for the treatment of hypotension were significantly less in patients who were preloaded with 6% hetastarch prior to cesarean section. The neonatal outcome, as determined by Apgar scores was good and similar in both groups.Conclusion:Hence, we conclude that 6% hydroxyl ethyl starch is more effective than lactated Ringers solution and that its routine use for preloading prior to spinal anesthesia should be considered.

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“…In our study, since the interval between preloading with colloid and spinal anesthesia was 30 min, there was more time for the osmotic effect of colloid (with 30 min as preloading time) to increase total volume which have been responsible for better prevention of decrease in SBP in colloid group, when compared to other groups. [ 14 ]…”

Section: Discussionmentioning

confidence: 99%

Comparison of the effects of colloid preload, vasopressor administration and leg compression on hemodynamic changes during spinal anesthesia for lumbar disc surgery in knee–chest position

Fani

Hirmanpour

2015

Adv Biomed Res

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Comparison of intravenous colloid and colloid-crystalloid combination in hypotension prophylaxis during spinal anesthesia for cesarean section

Abstract: Beyond 10 min the crystalloid-colloid combination has no advantage over colloid alone in hypotension prophylaxis, as used in this study.

Cited by 8 publications

References 14 publications

Association of hemodynamics during caesarean section, outcomes after caesarean section and hormone changes with different anesthesia in pregnant women with severe pulmonary arterial hypertension

Association of hemodynamics during caesarean section, outcomes after caesarean section and hormone changes with different anesthesia in pregnant women with severe pulmonary arterial hypertension

Six percent hetastarch versus lactated Ringer's solution – for preloading before spinal anesthesia for cesarean section

Comparison of the effects of colloid preload, vasopressor administration and leg compression on hemodynamic changes during spinal anesthesia for lumbar disc surgery in knee–chest position

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