Comparison of Intravascular Ultrasound with Conventional Venography for Detection of Extracranial Venous Abnormalities Indicative of Chronic Cerebrospinal Venous Insufficiency

Karmon, Yuval; Zivadinov, Robert; Weinstock‐Guttman, Bianca; Marr, Karen; Valnarov, Vesela; Dolić, Krešimir; Kennedy, Cheryl; Hojnacki, David; Carl, Ellen; Hagemeier, Jesper; Hopkins, L. Nelson; Levy, Elad I.; Siddiqui, Adnan H.

doi:10.1016/j.jvir.2013.06.012

Cited by 26 publications

(57 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…IVUS has revealed even more lesions than catheter venography, since CCSVI seems to be principally an endoluminal disease. 21,[28][29][30][31] This is probably the reason why investigators who utilized nondiluted contrast found less frequent (55%-70%) pathology in patients with multiple sclerosis. 32,33 Also, it should be remembered that catheter venography is inadequate to demonstrate external compression of the IJVs by aberrant muscles, because radiologic contrast injected into the vein, even under low pressure, can easily reopen a compressed vein.…”

Section: Results Of Catheter Venography and Ivusmentioning

confidence: 99%

“…30,[42][43][44] Further, current magnetic resonance imaging is not very good at demonstrating pathology of the jugular valves (catheter venography studies tell us that this is the most common CCSVI abnormality). 25,[27][28][29]45 These valves are tiny structures, which are not easily visible on standard magnetic resonance images. Also, artifacts resulting from respiratory and cardiac movements routinely blur the area of the jugular valves, as does gadolinium contrast.…”

Section: Figurementioning

confidence: 99%

“…57,114 Still, the pathology that is most often seen is a stenotic "over-competent" jugular valve. 25,[27][28][29]45,57,66,77 Such a pathological valve has been found in 70%-90% of patients with multiple sclerosis and also in many healthy controls. 33,35 Considering these many faces of CCSVI, it becomes more comprehensible why the results of prevalence studies have been so discordant.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Chronic cerebrospinal venous insufficiency: current perspectives

Simka¹

2014

JVD

View full text Add to dashboard Cite

Section: Results Of Catheter Venography and Ivusmentioning

confidence: 99%

Section: Figurementioning

confidence: 99%

mentioning

confidence: 99%

See 1 more Smart Citation

Chronic cerebrospinal venous insufficiency: current perspectives

Simka¹

2014

JVD

View full text Add to dashboard Cite

“…Unfortunately, published guidelines do not give a clear definition of such pathological intraluminal structures [12,20]. Undoubtedly, this part of sonographic assessment of IJVs needs clarification, and perhaps intravascular ultrasound (IVUS), instead of standard sonography, should be used to distinguish normal from pathological valves [16,29,30].…”

Section: Discussionmentioning

confidence: 99%

Diagnostic accuracy of Doppler sonography and magnetic resonance venography for the assessmentv of impaired outflow from the internal jugular vein in patients with multiple sclerosis

Hartel¹,

Kluczewska²,

Simka³

2015

View full text Add to dashboard Cite

Objectives: This prospective study was aimed at evaluation of diagnostic value of Doppler sonography and magnetic resonance (MR) venography in the internal jugular vein territory. Material and methods: There were assessed 126 patients (252 internal jugular veins). The patients were initially diagnosed using Doppler sonography and MR venography, and then catheter venography of the veins was performed. For the purpose of this study catheter venography was regarded the reference test. We interpreted sonographic findings in the context of criteria proposed by Zamboni and criteria by International Society for Neurovascular Disease (ISNVD). We applied MR protocols aimed at flow assessment in the scanned veins: fast spin echo-T2-weighted sequences with fat saturation, and axial two-dimensional time-of-flight imaging with saturation band positioned below planned slices. Results: Catheter venography revealed lesions in 171 (67.9%) of the veins studied, primarily stenotic jugular valves (88.0% of abnormal veins). We found that sonographic criteria, using either Zamboni or ISNVD criteria were of poor diagnostic accuracy (Cohen's k coefficient < 0.1). MR venography with the use of our dedicated protocols appeared to be a slightly better diagnostic tool (k about 0.4). Conclusions:The results of our MR imaging protocols for the assessment of abnormalities in internal jugular veins were better if compared to Doppler sonography. Yet, even MR venography was far from being perfect and at the moment neither this examination nor Doppler sonography cannot replace invasive catheter venography and should not be used as a definitive test for diagnosing anatomical and functional abnormalities in the internal jugular veins.

show abstract

“…According to these authors, the vascular occlusive lesions characteristic of CCSVI are truncular malformations that can be clearly demonstrated by selective catheter venography [5]. Since the inception of CCSVI [5], several venographic protocols to evaluate the jugular and azygos veins have been described in recent publications [1,4,[6][7][8][9][10][11][12]; however, none of these have been validated, and to the present time there is no venographic protocol that has been accepted as a standard in the evaluation of this condition [1,12].…”

Section: Introductionmentioning

confidence: 99%

Review of catheter venography protocols in the evaluation of chronic cerebrospinal venous insufficiency

Ferral¹

2014

View full text Add to dashboard Cite

Catheter venography has been considered to be the "gold standard" in the evaluation of venous pathology. Chronic cerebrospinal venous insufficiency (CCSVI) has recently been described as a condition characterised by the presence of multiple stenotic lesions of the main pathways of extracranial venous drainage, especially the internal jugular veins and the azygos vein. The primary screening diagnostic method to identify the venous lesions has been Doppler sonography. Once the abnormalities are identified by the non-invasive method, patients undergo catheter venography to confirm the presence of venous lesions with the aim of performing treatment, which has mainly been balloon angioplasty. Since the inception of CCSVI, several venographic protocols to evaluate the internal jugular and azygos veins have been described, but none of them have been scientifically validated. The purpose of this review is to analyse the most recent catheter venography protocols reported for the diagnosis and management of CCSVI. The materials and methods sections of the most recently published series describing catheter venography for the evaluation and management for CCSVI were reviewed. The technical details, including venous access selection site, catheter selection, ideal catheter position, contrast injection techniques, and interpretation of venographic findings, were reviewed. Comments on each of the technical factors are presented. Final comments with proposed techniques are presented.

show abstract

Comparison of Intravascular Ultrasound with Conventional Venography for Detection of Extracranial Venous Abnormalities Indicative of Chronic Cerebrospinal Venous Insufficiency

Cited by 26 publications

References 33 publications

Chronic cerebrospinal venous insufficiency: current perspectives

Chronic cerebrospinal venous insufficiency: current perspectives

Diagnostic accuracy of Doppler sonography and magnetic resonance venography for the assessmentv of impaired outflow from the internal jugular vein in patients with multiple sclerosis

Review of catheter venography protocols in the evaluation of chronic cerebrospinal venous insufficiency

Contact Info

Product

Resources

About