Comparison of intracoronary Doppler guide wire and transesophageal echocardiography in measurement of flow velocity and coronary flow reserve in the left anterior descending coronary artery

Gadallah, Sameh; Thaker, Kartik B.; Kawanishi, David T.; Mehra, Anilkumar; Lau, Stanley K.; Rashtian, Mayer; Chandraratna, P.A.N.

doi:10.1016/s0002-8703(98)70340-0

Cited by 31 publications

(18 citation statements)

References 9 publications

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“…As a non-invasive method that evaluates CFR by measuring the flow velocity in the left anterior descending coronary artery, TEE has been used actively in clinical settings [21 -23]. After Gadallah et al [23] reported that CFR measured by TEE showed very good correlation with the invasive method using Doppler-tip guide wire, TEE became an important noninvasive method in evaluating CFR.…”

Section: Discussionmentioning

confidence: 99%

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Relation between Duke treadmill score and coronary flow reserve using transesophageal Doppler echocardiography in patients with microvascular angina

Youn

Park

Moon

et al. 2005

International Journal of Cardiology

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Section: Discussionmentioning

confidence: 99%

“…Thus, the accuracy of this semi-invasive technique for measuring absolute values of coronary flow velocity remains to be demonstrated. However, Gadallah et al [23] already reported that CFR measured by TEE showed a very good correlation with the invasive method using Doppler-tip guide wire.…”

Section: Limitationsmentioning

confidence: 94%

Relation between Duke treadmill score and coronary flow reserve using transesophageal Doppler echocardiography in patients with microvascular angina

Youn

Park

Moon

et al. 2005

International Journal of Cardiology

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“…Quantitatively, the simulated mean diastolic/systolic flow velocity ratio in the LAD was 1.88, which was close to the clinical data (1.8 ± 0.5) measured in patients with normal coronary perfusion . Under the hyperemic conditions, in addition to a marked increase in total blood flow rate through the coronary arteries, there were significant changes in flow waveform, such as the increased peak flow in systole (see Figure B), which agreed qualitatively with clinical observations …”

Section: Resultsmentioning

confidence: 99%

A multi‐scale model of the coronary circulation applied to investigate transmural myocardial flow

Yin

Fan

et al. 2018

Numer Methods Biomed Eng

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Distribution of blood flow in myocardium is a key determinant of the localization and severity of myocardial ischemia under impaired coronary perfusion conditions. Previous studies have extensively demonstrated the transmural difference of ischemic vulnerability. However, it remains incompletely understood how transmural myocardial flow is regulated under in vivo conditions. In the present study, a computational model of the coronary circulation was developed to quantitatively evaluate the sensitivity of transmural flow distribution to various cardiovascular and hemodynamic factors. The model was further incorporated with the flow autoregulatory mechanism to simulate the regulation of myocardial flow in the presence of coronary artery stenosis. Numerical tests demonstrated that heart rate (HR), intramyocardial tissue pressure (P ), and coronary perfusion pressure (P ) were the major determinant factors for transmural flow distribution (evaluated by the subendocardial-to-subepicardial (endo/epi) flow ratio) and that the flow autoregulatory mechanism played an important compensatory role in preserving subendocardial perfusion against reduced P . Further analysis for HR variation-induced hemodynamic changes revealed that the rise in endo/epi flow ratio accompanying HR decrease was attributable not only to the prolongation of cardiac diastole relative to systole, but more predominantly to the fall in P . Moreover, it was found that P and P interfered with each other with respect to their influence on transmural flow distribution. These results demonstrate the interactive effects of various cardiovascular and hemodynamic factors on transmural myocardial flow, highlighting the importance of taking into account patient-specific conditions in the explanation of clinical observations.

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“…Correlations with invasive techniques have proved very good. 22 Results may further improve with contrast echocardiography.…”

Section: Simpler Inexpensive Non-invasive Diagnostic Modalitiesmentioning

confidence: 96%

Coronary flow: clinical considerations

Cokkinos

2003

Heart

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Comparison of intracoronary Doppler guide wire and transesophageal echocardiography in measurement of flow velocity and coronary flow reserve in the left anterior descending coronary artery

Cited by 31 publications

References 9 publications

Relation between Duke treadmill score and coronary flow reserve using transesophageal Doppler echocardiography in patients with microvascular angina

Relation between Duke treadmill score and coronary flow reserve using transesophageal Doppler echocardiography in patients with microvascular angina

A multi‐scale model of the coronary circulation applied to investigate transmural myocardial flow

Coronary flow: clinical considerations

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