Comparison of Impella and intra-aortic balloon pump in high-risk percutaneous coronary intervention: Vascular complications and incidence of bleeding

Boudoulas, Konstantinos Dean; Pederzolli, Andrew; Saini, Uksha; Gumina, Richard J.; Mazzaferri, Ernest L.; Davis, Michael; Bush, Charles A.; Capers, Quinn; Magorien, Raymond D.; Pompili, Vincent J.

doi:10.3109/17482941.2012.741244

Cited by 26 publications

(20 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the controlled observational studies, the 30‐day rates of all‐cause mortality were higher in the Impella arm than in the IABP arm in 2 of the 3 studies that reported this endpoint (Table ) . However, neither reached statistical significance due to their modest sample sizes.…”

Section: Resultsmentioning

confidence: 96%

See 1 more Smart Citation

The effectiveness and safety of the Impella ventricular assist device for high‐risk percutaneous coronary interventions: A systematic review

Ichou

Larivée

Eisenberg

et al. 2017

Cathet Cardio Intervent

View full text Add to dashboard Cite

show abstract

Section: Resultsmentioning

confidence: 96%

“…Several studies have examined the effectiveness and safety of the Impella device . However, many of these studies were small and produced inconclusive results.…”

Section: Introductionmentioning

confidence: 99%

The effectiveness and safety of the Impella ventricular assist device for high‐risk percutaneous coronary interventions: A systematic review

Ichou

Larivée

Eisenberg

et al. 2017

Cathet Cardio Intervent

View full text Add to dashboard Cite

show abstract

“…A single-center study of ECLS in cardiogenic shock reported bleeding complications in 17.4% and need for surgical intervention in 8.7% of all patients [23] while registry data for ECLS in cardiopulmonary resuscitation report complications directly related to ECLS implantation in every third patient [16]. Concerning blood transfusions after device implantation, a recent meta-analysis reported a transfusion in 32 to 38% of all patients after IABP or Impella 2.5 implantation, respectively [24]. …”

Section: Discussionmentioning

confidence: 99%

Unprotected Left Main Percutaneous Coronary Intervention in Acute Coronary Syndromes with Extracorporeal Life Support Backup

et al. 2015

View full text Add to dashboard Cite

Background. Left main PCI is superior to coronary bypass surgery in selected patients. Registry data, however, suggest significant early adverse event rates associated with unprotected left main PCI. We aimed to evaluate safety of an extracorporeal life support (ECLS) as backup system during PCI. Methods. We report a registry study of 16 high-risk patients presenting with acute coronary syndromes undergoing unprotected left main PCI with an ECLS backup. Results. Seven patients (43.8%) presented with an acute myocardial infarction while 9 patients (56.3%) had unstable angina. Unprotected left main PCI could be successfully performed in all 16 patients. Mortality or thromboembolic event rates were zero within the index hospital stay. General anesthesia was necessary only in 5 patients (31.3%). Access site bleeding requiring transfusion was encountered in 4 patients (25.0%). Three patients (18.8%) developed access site complications requiring surgical intervention. All patients were ECLS-free after 96 hours. Conclusions. Unprotected left main PCI could be safely and effectively performed after ECLS implantation as backup in acute coronary syndromes in our patient collectively. Vascular access site complications however need to be considered when applying ECLS as backup system.

show abstract

“…The major complications of using the device are vascular injury, hemolysis, thrombocytopenia, and impairment of valve function [13,14]. Mild hemolysis was suspected in this case, but it was not severe enough to require early discontinuation of the device, nor blood transfusion.…”

Section: Discussionmentioning

confidence: 94%

Massive Atenolol, Lisinopril, and Chlorthalidone Overdose Treated with Endoscopic Decontamination, Hemodialysis, Impella Percutaneous Left Ventricular Assist Device, and ECMO

et al. 2014

View full text Add to dashboard Cite

Background Overdose of cardiovascular medications is increasingly associated with morbidity and mortality. We present a case of substantial atenolol, chlorthalidone, and lisinopril overdose treated by multiple modalities with an excellent outcome. Conclusion Aggressive medical intervention did not provide sufficient hemodynamic stability in this patient with refractory cardiogenic and distributive shock. Impella® percutaneous left ventricular assist device and extracorporeal membrane oxygenation provided support while the effects of the overdose subsided. We present concentrations demonstrating removal of atenolol with continuous venovenous hemodiafiltration. This is the first report of esophagogastroduo denoscopy decontamination of this overdose with a large pill fragment burden.

show abstract

Comparison of Impella and intra-aortic balloon pump in high-risk percutaneous coronary intervention: Vascular complications and incidence of bleeding

Abstract: Impella can be used as safely as IABP during high-risk PCI with similar vascular and bleeding complications. Importantly, approximately one third of bleeding was from the gastrointestinal system warranting careful prophylactic measures and monitoring.

Cited by 26 publications

References 16 publications

The effectiveness and safety of the Impella ventricular assist device for high‐risk percutaneous coronary interventions: A systematic review

The effectiveness and safety of the Impella ventricular assist device for high‐risk percutaneous coronary interventions: A systematic review

Unprotected Left Main Percutaneous Coronary Intervention in Acute Coronary Syndromes with Extracorporeal Life Support Backup

Massive Atenolol, Lisinopril, and Chlorthalidone Overdose Treated with Endoscopic Decontamination, Hemodialysis, Impella Percutaneous Left Ventricular Assist Device, and ECMO

Contact Info

Product

Resources

About