Comparison of image noise and image quality between full-dose abdominal computed tomography scans reconstructed with weighted filtered back projection and half-dose scans reconstructed with improved sinogram-affirmed iterative reconstruction (SAFIRE*)

Choy, Suelynn; Parhar, Dennis; Lian, Kevin; Schmiedeskamp, Heiko; Louis, Luck J.; O’Connell, Timothy; McLaughlin, Patrick D.; Nicolaou, Savvas

doi:10.1007/s00261-018-1687-9

Cited by 6 publications

(8 citation statements)

References 26 publications

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“…The aim of the study was to find the optimal IR strength and the lowest possible (reference) tube current that could be used in abdominal CT imaging, without compromising objective and subjective image quality. In accordance with the literature, IR techniques outperformed FBP [ 18 , 19 , 22 ]. When IR techniques are used, the mAs ref can be reduced without compromising objective image quality.…”

Section: Discussionsupporting

confidence: 88%

“…Previous studies have shown IR techniques to be superior to filtered back projection (FBP). Although, while Hardie et al showed a reader preference for low to intermediate IR strengths, Choy et al demonstrated a preference for images reconstructed with IR strength 4 or 5 [ 18 , 19 ]. Noise decreases with an increased IR strength, but at the same time, the texture of the noise changes, possibly negatively influencing image quality [ 20 ].…”

Section: Introductionmentioning

confidence: 99%

“…Therefore, in daily clinical practice, different IR strengths are used, which may also depend on the scan phase (e.g. arterial, portal venous or delayed phase) [ 18 , 21 – 23 ].…”

Section: Introductionmentioning

confidence: 99%

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Finding the optimal tube current and iterative reconstruction strength in liver imaging; two needles in one haystack

et al. 2022

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Objectives The aim of the study was to find the lowest possible tube current and the optimal iterative reconstruction (IR) strength in abdominal imaging. Material and methods Reconstruction software was used to insert noise, simulating the use of a lower tube current. A semi-anthropomorphic abdominal phantom (Quality Assurance in Radiology and Medicine, QSA-543, Moehrendorf, Germany) was used to validate the performance of the ReconCT software (S1 Appendix). Thirty abdominal CT scans performed with a standard protocol (120 kVref, 150 mAsref) scanned at 90 kV, with dedicated contrast media (CM) injection software were selected. There were no other in- or exclusion criteria. The software was used to insert noise as if the scans were performed with 90, 80, 70 and 60% of the full dose. Consequently, the different scans were reconstructed with filtered back projection (FBP) and IR strength 2, 3 and 4. Both objective (e.g. Hounsfield units [HU], signal to noise ratio [SNR] and contrast to noise ratio [CNR]) and subjective image quality were evaluated. In addition, lesion detection was graded by two radiologists in consensus in another 30 scans (identical scan protocol) with various liver lesions, reconstructed with IR 3, 4 and 5. Results A tube current of 60% still led to diagnostic objective image quality (e.g. SNR and CNR) when IR strength 3 or 4 were used. IR strength 4 was preferred for lesion detection. The subjective image quality was rated highest for the scans performed at 90% with IR 4. Conclusion A tube current reduction of 10–40% is possible in case IR 4 is used, leading to the highest image quality (10%) or still diagnostic image quality (40%), shown by a pairwise comparison in the same patients.

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Section: Discussionsupporting

confidence: 88%

Section: Introductionmentioning

confidence: 99%

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Finding the optimal tube current and iterative reconstruction strength in liver imaging; two needles in one haystack

et al. 2022

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“…A recent retrospective study comparing a novel IR algorithm improved sinogram-affirmed iterative reconstruction (SAFIRE ∗ , Siemens Healthcare, Erlangen, Germany), with the standard filtered back projection (FBP). It was found that half-dose CT datasets reconstructed with SAFIRE ∗ maintained acceptable image quality compared with full-dose CT datasets reconstructed with FBP [ 76 ]. The IR algorithm in this case, though a research-only prototype currently, potentially allows dose reductions in the order of 50% over conventional CT scans.…”

Section: Computed Tomographymentioning

confidence: 99%

Low-Dose Computed Tomography for the Optimization of Radiation Dose Exposure in Patients with Crohn’s Disease

Kavanagh

O’Grady

Carey

et al. 2018

Gastroenterology Research and Practice

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Magnetic resonance imaging (MRI) is the mainstay method for the radiological imaging of the small bowel in patients with inflammatory bowel disease without the use of ionizing radiation. There are circumstances where imaging using ionizing radiation is required, particularly in the acute setting. This usually takes the form of computed tomography (CT). There has been a significant increase in the utilization of computed tomography (CT) for patients with Crohn's disease as patients are frequently diagnosed at a relatively young age and require repeated imaging. Between seven and eleven percent of patients with IBD are exposed to high cumulative effective radiation doses (CEDs) (>35–75 mSv), mostly patients with Crohn's disease (Newnham E 2007, Levi Z 2009, Hou JK 2014, Estay C 2015). This is primarily due to the more widespread and repeated use of CT, which accounts for 77% of radiation dose exposure amongst patients with Crohn's disease (Desmond et al., 2008). Reports of the projected cancer risks from the increasing CT use (Berrington et al., 2007) have led to increased patient awareness regarding the potential health risks from ionizing radiation (Coakley et al., 2011). Our responsibilities as physicians caring for these patients include education regarding radiation risk and, when an investigation that utilizes ionizing radiation is required, to keep radiation doses as low as reasonably achievable: the “ALARA” principle. Recent advances in CT technology have facilitated substantial radiation dose reductions in many clinical settings, and several studies have demonstrated significantly decreased radiation doses in Crohn's disease patients while maintaining diagnostic image quality. However, there is a balance to be struck between reducing radiation exposure and maintaining satisfactory image quality; if radiation dose is reduced excessively, the resulting CT images can be of poor quality and may be nondiagnostic. In this paper, we summarize the available evidence related to imaging of Crohn's disease, radiation exposure, and risk, and we report recent advances in low-dose CT technology that have particular relevance.

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“…e sinogram affirmed iterative reconstruction (SAFIRE) algorithm is a new iterative reconstruction algorithm developed by Siemens, which is an iterative reconstruction algorithm based on the original data [11]. It can extremely reduce the noises of CT images and has a significant effect on the removal of spiral CTartifacts.…”

Section: Introductionmentioning

confidence: 99%

Values of Sinogram Affirmed Iterative Reconstruction Algorithm-Based Low-Dose Computed Tomography Imaging in Clinical Diagnosis of Cerebral Hemorrhage

Wang

Chen

Fang

et al. 2021

Scientific Programming

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In this study, the sinogram affirmed iterative reconstruction (SAFIRE) technology combined with low-dose computed tomography (CT) scanning technology was applied to scan patients with cerebral hemorrhage to evaluate the application value of this combined technology in the diagnosis of patients with cerebral hemorrhage. 132 patients with cerebral hemorrhage admitted to the hospital were selected randomly as the research objects in this study. According to the patients’ wishes, all of them were rolled into an experimental group and a control group. Besides, patients who were willing to use low-dose CT imaging scanning technology based on the SAFIRE algorithm were classified into the experimental group, and those who received simple low-dose CT scans were classified into the control group. Subjective score, objective score (mean CT value), image noise (SD), signal-to-noise ratio (SNR), and contrast-noise ratio (CNR) were used to analyze and compare the two groups of detection methods. The results showed the following: (1) The average result of CT images was 4.05 ± 0.28 points for the control group and 4.43 ± 0.59 points for the experimental group. According to the classification, the excellent and good rates of the experimental group (89.9%) were markedly higher than the rates of the control group (65.8%), with a statistically obvious difference ( P < 0.05). (2) The standard deviation (SD), image signal-to-noise ratio (SNR), and contrast-noise ratio (CNR) results of gray matter, white matter, and cerebral hemorrhage lesions of patients from the experimental group were better than those of the control group, and the differences were statistically significant ( P < 0.05). In conclusion, the image quality of a low-dose CT scan reconstructed by the SAFIRE algorithm was superior to that of a simple low-dose CT scan. In other words, the image quality of CT images could be guaranteed by the SAFIRE technology under the condition of reducing radiation dose. It enabled patients with cerebral hemorrhage to carry out diagnostic examinations with guaranteed accuracy under the risk of low radiation and provided better imaging services for patients with cerebral hemorrhage.

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Comparison of image noise and image quality between full-dose abdominal computed tomography scans reconstructed with weighted filtered back projection and half-dose scans reconstructed with improved sinogram-affirmed iterative reconstruction (SAFIRE*)

Abstract: Half-dose CT images reconstructed with SAFIRE* at strength 4 and 5 have superior image quality compared to full-dose images reconstructed with wFBP. SAFIRE* potentially allows dose reductions in the order of 50% over wFBP.

Cited by 6 publications

References 26 publications

Finding the optimal tube current and iterative reconstruction strength in liver imaging; two needles in one haystack

Finding the optimal tube current and iterative reconstruction strength in liver imaging; two needles in one haystack

Low-Dose Computed Tomography for the Optimization of Radiation Dose Exposure in Patients with Crohn’s Disease

Values of Sinogram Affirmed Iterative Reconstruction Algorithm-Based Low-Dose Computed Tomography Imaging in Clinical Diagnosis of Cerebral Hemorrhage

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