Comparison of Hysterosalpingography and Laparoscopy as Diagnostic Tool for Tubal Infertility in Bangladesh

Abstract

Background: Tubal evaluation is an integral part of the evaluation of female infertility. Hysterosalpingography (HSG) is the radiographic evaluation of the uterus and fallopian tubes, which has been used as a first-line test for tubal assessment since 1920s. Laparoscopy is considered to be the gold standard for the diagnosis and management of tubo-peritoneal pathology. The objective of this study is to evaluate and compare the diagnostic value of both HSG and laparoscopy for assessment of tubal occlusion. Methods: This is a prospective cross-sectional study. Laparoscopic chromopertubation was conducted on 125 consecutive infertile women who attended the “Infertility Management Center” from October 2018 to September 2019. All patients had HSG performed in the radiology department of different hospitals. Laparoscopic findings were used as a reference standard to analyze the findings of HSG for tubal occlusion. Data were analyzed by SPSS software (version 16). Results: Normal HSG findings were seen in 53 patients (42.4%). Unilateral tubal occlusion was present in 38 (30.7%), and bilateral occlusion in 34 (27.2%) patients. Laparoscopy showed normal findings in 85 (68.0%) patients. Unilateral tubal occlusion was demonstrated in laparoscopy in 27 (21.6%) and bilateral tubal occlusion in 13 (10.4%) patients. HSG findings for diagnosis of tubal occlusion was true positive in 30 (24%) cases, false positive in 42 (33.6%) cases, false negative in 10 (8%) cases, and true negative in 43 (34.4%) cases in comparison to laparoscopy findings. Sensitivity of HSG was found to be 75.0%, specificity 50.6%, and accuracy 58.4%. Positive predictive value and negative predictive value were 41.7% and 81.1%, respectively. Conclusion: HSG is widely used for tubal assessment in Bangladesh as it is a relatively inexpensive, low-risk office procedure. But it has a low specificity and positive predictive value with a relatively high negative predictive value. Laparoscopy, on the other hand, is preferable when there is high suspicion of tubal pathology.

The diagnostic value of hysterosalpingo-contrast sonography in female infertility of the fallopian tube

“…The sensitivity and negative predictive values presented here are lower than those reported by Gundu Z 11 and Chowdhury. 13 However, their accuracy, specificity and positive predictive value are higher than those reported by Gundu Z and Chowdhury, but their specificity and negative predictive value are similar to those reported by Foroozanfard. 11,13,14 Laparoscopy is the gold standard for the diagnosis of tubal diseases, and clearly shows the morphology of fallopian tubes, comprehensively observes the peristalsis of fallopian tubes, pelvic cavity and other conditions.…”

“…13 However, their accuracy, specificity and positive predictive value are higher than those reported by Gundu Z and Chowdhury, but their specificity and negative predictive value are similar to those reported by Foroozanfard. 11,13,14 Laparoscopy is the gold standard for the diagnosis of tubal diseases, and clearly shows the morphology of fallopian tubes, comprehensively observes the peristalsis of fallopian tubes, pelvic cavity and other conditions. Both laparoscopy and HyCoSy have good consistency in the diagnosis of proximal and distal fallopian tube obstruction, but the specificity and sensitivity are not ideal.…”

“…The sensitivity and negative predictive values presented here are lower than those reported by Gundu Z 11 and Chowdhury. 13 However, their accuracy, specificity and positive predictive value are higher than those reported by Gundu Z and Chowdhury, but their specificity and negative predictive value are similar to those reported by Foroozanfard. 11 , 13 , 14 …”

“… 13 However, their accuracy, specificity and positive predictive value are higher than those reported by Gundu Z and Chowdhury, but their specificity and negative predictive value are similar to those reported by Foroozanfard. 11 , 13 , 14 …”