Comparison of Horizontal Corneal Diameter Measurements Using the Orbscan IIz and Pentacam HR Systems

Salouti, Ramin; Nowroozzadeh, Mohammad Hossein; Zamani, Mohammad; Ghoreyshi, Maryam; Khodaman, Amir R.

doi:10.1097/ico.0b013e3182a40786

Cited by 48 publications

(41 citation statements)

References 17 publications

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“…In addition to thin corneas, mice and rats have corneas that are quite small in diameter compared to people (approximately 2 mm versus 11 mm respectively) (Henriksson et al 2009, Salouti et al 2013). Due to their small diameter it can be difficult to isolate the axial cornea when performing an alkali burn.…”

Section: Discussionmentioning

confidence: 99%

Development of a novel in vivo corneal fibrosis model in the dog

Gronkiewicz

Giuliano

Kuroki

et al. 2016

Experimental Eye Research

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The aim of this study was to develop a novel in vivo corneal model of fibrosis in dogs utilizing alkali burn and determine the ability of suberanilohydroxamic acid (SAHA) to inhibit corneal fibrosis using this large animal model. To accomplish this, we used seven research Beagle dogs. An axial corneal alkali burn in dogs was created using 1 N NaOH topically. Six dogs were randomly and equally assigned into 2 groups: A) vehicle (DMSO, 2 μL/mL); B) anti-fibrotic treatment (50 μM SAHA). The degree of corneal opacity, ocular health, and anti-fibrotic effects of SAHA were determined utilizing the Fantes grading scale, modified McDonald-Shadduck (mMS) scoring system, optical coherence tomography (OCT), corneal histopathology, immunohistochemistry (IHC), and transmission electron microscopy (TEM). The used alkali burn dose to produce corneal fibrosis was well tolerated as no significant difference in mMS scores between control and treatment groups (p=0.89) were detected. The corneas of alkali burned dogs showed significantly greater levels of α-smooth muscle actin, the fibrotic marker, than the controls (p=0.018). Total corneal thickness of all dogs post-burn was significantly greater than baseline OCT images irrespective of treatment (p=0.004); TEM showed that alkali burned corneas had significantly greater minimum and maximum interfibrillar distances than the controls (p=0.026, p=0.018). The tested topical corneal alkali burn dose generated significant opacity and fibrosis in dog corneas without damaging the limbus as evidenced by histopathology, IHC, TEM, and OCT findings, and represents a viable large animal corneal fibrosis in vivo model. Additional in vivo SAHA dosing studies with larger sample size are warranted.

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Section: Discussionmentioning

confidence: 99%

Development of a novel in vivo corneal fibrosis model in the dog

Gronkiewicz

Giuliano

Kuroki

et al. 2016

Experimental Eye Research

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“…Accurate IOL power calculation particularly depends on accurate measurement of corneal keratometry readings ( K 1, K 2) and anterior chamber depth (ACD) and axial length (AL) values [4, 5]. Accurate measurement of pupil size (PS) and horizontal iris width (white-to-white [WTW]) values is another important factor that increases the success of cataract and refractive surgery [6–9]. …”

Section: Introductionmentioning

confidence: 99%

Evaluation of the Repeatability and the Reproducibility of AL-Scan Measurements Obtained by Residents

Kola

Duran

Türk

et al. 2014

Journal of Ophthalmology

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Purpose. To assess the repeatability and reproducibility of ocular biometry and intraocular lens (IOL) power measurements obtained by ophthalmology residents using an AL-Scan device, a novel optical biometer. Methods. Two ophthalmology residents were instructed regarding the AL-Scan device. Both performed ocular biometry and IOL power measurements using AL-Scan, three times on each of 128 eyes, independently of one another. Corneal keratometry readings, horizontal iris width, central corneal thickness, anterior chamber depth, pupil size, and axial length values measured by both residents were recorded together with IOL power values calculated on the basis of four different IOL calculation formulas (SRK/T, Holladay, and HofferQ). Repeatability and reproducibility of the measurements obtained were analyzed using the intraclass correlation coefficient (ICC). Results. Repeatability (ICC, 0.872-0.999 for resident 1 versus 0.905-0.999 for resident 2) and reproducibility (ICC, 0.916-0.999) were high for all biometric measurements. Repeatability (ICC, 0.981-0.983 for resident 1 versus 0.995-0.996 for resident 2) and reproducibility were also high for all IOL power measurements (ICC, 0.996 for all). Conclusions. The AL-Scan device exhibits good repeatability and reproducibility in all biometric measurements and IOL power calculations, independent of the operator concerned.

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“…A study undertaken previously showed that the repeatability and reproducibility of AL-Scan is excellent in terms of all parameters, except the WTW and PD and compares favorably with the IOL Master 22 . Another study also found that the repeatability and reproducibility of both devices were high for all ocular biometry measurements tested except for the WTW corneal diameter 23 . Both these studies also showed that the IOL power calculation was similar with the AL-scan and IOL Master.…”

Section: Discussionmentioning

confidence: 86%

Refractive results after cataract surgery using Optical biometry

Hussain¹,

Quraishy²,

Akram³

2020

pak J Ophthalmol

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Purpose: To assess the refractive outcome of optical biometry (Nidek AL-scan) after elective phacoemulsification in a study of 30 eyes. Study Design: Descriptive case series. Place and Duration of Study: Elective cataract surgeries done at a private clinic from July 2015 to June 2016 were selected and their records were analyzed. Material Methods: The measurements of IOL calculation was done using optical biometry with partial coherence interferometry (Nidek AL-scan) that provides information about axial length, central keratometry, white to white diameter and anterior chamber anatomical depth. SRK-T formula was used to calculate IOL power. All patients underwent a complete ophthalmological examination. Phacoemulsification with clear corneal incision of 2.75 mm was done and IOL was implanted in the bag (Alcon Acrysof SN60WF IOL and MA60AC IOL). Post-operative refraction was taken with autorefractor (Huvitz HRK-7000) after 4 weeks and it was compared with pre-operative objective refraction. Comparison of K readings taken by AL-scan and autorefractor were done. Results: We studied 30 eyes of 23 patients who underwent elective cataract surgery with foldable IOL. Post-operative spherical equivalent was plano in 53% of cases with mean of -0.05 after 4 weeks postoperatively. The mean keratometric power using autorefractor was 44.4 D while with AL-scan it was 44.7 D. There were no intraoperative complications or postoperative subjective complaints (such as halo or glare) in our patients. Conclusion: Intraocular lens power calculations done by optical biometry are easy to use, reliable and result in excellent refractive outcomes. Ultrasound biometry may still be required in case of mature and dense posterior subcapsular cataract.

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Comparison of Horizontal Corneal Diameter Measurements Using the Orbscan IIz and Pentacam HR Systems

Abstract: The observed differences in WTW distance readings between the Pentacam HR and the Orbscan IIz are not clinically relevant, and the 2 devices could be used interchangeably in clinical practice.

Cited by 48 publications

References 17 publications

Development of a novel in vivo corneal fibrosis model in the dog

Development of a novel in vivo corneal fibrosis model in the dog

Evaluation of the Repeatability and the Reproducibility of AL-Scan Measurements Obtained by Residents

Refractive results after cataract surgery using Optical biometry

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