2015
DOI: 10.1590/s0102-6720201500040014
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Comparison of Hepatic Profile in Pre and Postoperative of Bariatric Surgery: Private vs Public Network

Abstract: Background: Obesity is associated to several comorbidities, including nonalcoholic fatty liver disease, which implicates in isolated steatosis to steatohepatitis. The latter may progress to severe manifestations such as liver fibrosis, cirrhosis and hepatocellular carcinoma. Aim: To compare the presence of advanced liver fibrosis before and after bariatric surgery in patients of private and public health system. Methods: Patients from public and privative networks were studied before and after bariatric surger… Show more

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Cited by 10 publications
(6 citation statements)
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References 19 publications
(23 reference statements)
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“…Two recent meta-analyses have reported that RYGB had a positive effect on NAFLD after short- to mid-term follow-up time of 1–60 months, with improvement or resolution of histological steatosis and steatohepatitis in the majority of patients, as well as resolution of fibrosis in 28–51% [ 12 , 13 ]. Importantly, studies assessing resolution of liver fibrosis after RYGB with NFS and/or FIB-4 have found improvement in agreement with studies using biopsies [ 26 , 27 , 28 , 29 ]. The proportion of patients with a low postoperative fibrosis score was similar in our population to that in studies with shorter follow-up times [ 11 , 12 , 29 , 30 , 31 , 32 , 33 ].…”
Section: Discussionsupporting
confidence: 71%
“…Two recent meta-analyses have reported that RYGB had a positive effect on NAFLD after short- to mid-term follow-up time of 1–60 months, with improvement or resolution of histological steatosis and steatohepatitis in the majority of patients, as well as resolution of fibrosis in 28–51% [ 12 , 13 ]. Importantly, studies assessing resolution of liver fibrosis after RYGB with NFS and/or FIB-4 have found improvement in agreement with studies using biopsies [ 26 , 27 , 28 , 29 ]. The proportion of patients with a low postoperative fibrosis score was similar in our population to that in studies with shorter follow-up times [ 11 , 12 , 29 , 30 , 31 , 32 , 33 ].…”
Section: Discussionsupporting
confidence: 71%
“…Resection appears today as the main approach for treatment of HCC, especially in patients with good liver function. This mainly occurs because of the restrictive criteria and the inadequate supply of grafts for transplantation in the world 1 , 11 , 13 , 16 , 19 .…”
Section: Discussionmentioning
confidence: 99%
“…Nascimento et al analyzed changes in NAFLD Fibrosis Score before and after bariatric surgery. The NAFLD Fibrosis Score changed from −0.6845 before the surgery to −1.6898 12 months after the procedure (p < 0.0002), indicating an absence of advanced liver fibrosis in any patient 12 months after the surgery [35] In the above-mentioned study, a weak negative correlation between the decrease in NAFLD Fibrosis Score and weight loss parameters (%EWL (r = −0.251, p < 0.0001) and %TWL (r = −0.280, p < 0.0001)) was observed [37]. In our study, a statistically significant decrease in NAFLD Fibrosis Score was also seen.…”
Section: Discussionmentioning
confidence: 94%