Comparison of efficacy of tray-delivered carbamide and hydrogen peroxide for at-home bleaching: a systematic review and meta-analysis

Luque-Martínez, Issis; Reis, Alessandra; Schroeder, M.; Muñoz, Miguel Angel; Loguércio, Alessandro Dourado; Ferreira, Daniele Masterson Tavares Pereira; Maia, Lucianne Cople

doi:10.1007/s00784-016-1863-7

Cited by 86 publications

(87 citation statements)

References 48 publications

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“…The bleaching products are mostly based on hydrogen peroxide (HP) or one of its precursors, such as carbamide peroxide (CP) . Recent meta‐analysis has shown that CP is slightly better in terms of whitening effectiveness when compared to HP, demonstrating similar tooth sensitivity and gum irritation …”

Section: Introductionmentioning

confidence: 99%

“…6,7 Recent meta-analysis has shown that CP is slightly better in terms of whitening effectiveness when compared to HP, demonstrating similar tooth sensitivity and gum irritation. 8 Temperature is an important factor to be considered for bleaching products, because an increase of 10 C doubles the rate of chemical reaction, accelerating the bleaching treatment. 9 In this regard, the storage of bleaching agents at high temperatures can induce the dissociation of components, reducing the shelf life of these products.…”

Section: Introductionmentioning

confidence: 99%

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Effect of temperature and storage time on dental bleaching effectiveness

Chisini

Conde

Meireles

et al. 2018

J Esthet Restor Dent

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Objective To evaluate the effect of storage time and temperature on the effectiveness of bleaching agents. Methods Enamel slabs were randomly allocated according to the concentration of carbamide peroxide (CP): 10% (CP10) and 16% (CP16). Shade evaluations were conducted at baseline and then after 3 and 12 months of storage at 3 different temperatures: 10°C (±2°C), 25°C (±2°C), and 35°C (±2°C). Objective color evaluation was performed (spectrophotometer CIEL*a*b* system and CIEDE2000) to calculate the color change (ΔE00). Subjective evaluation was performed using the VITA classical shade guide followed by shade variation (ΔS). Results The bleaching effect of different CP concentrations (10% and 16%) at baseline showed no differences with regard to objective (ΔE00) and subjective parameters (ΔS) (P > .05). No differences were observed between CP concentrations stored for the same length of time and at the same temperature for either parameter (P > .05). In terms of objective measurement (ΔE00), a reduction in the bleaching effect was shown for both CP concentrations (10% and 16%) when stored for 12 months at 35°C, and compared with the baseline (P < .05). As regards the subjective parameters (ΔS), after 12 months, both CP concentrations (10% and 16%) stored at 35°C showed a decrease in bleaching capacity compared to baseline (P < .05). CP10 and CP16 stored at 10°C and 25°C did not suffer any loss in bleaching ability, even after 12 months (P > .05). Conclusions The storage of bleaching agents for long periods at high temperatures can reduce the bleaching effectiveness of CP at 10% and 16%. Clinical Significance Clinicians must be made aware that they should store their bleaching products under proper temperature conditions and use them within an appropriate time frame; otherwise, the bleaching effect could be lost.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Effect of temperature and storage time on dental bleaching effectiveness

Chisini

Conde

Meireles

et al. 2018

J Esthet Restor Dent

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“…Most studies on the optical properties of teeth have focused only on the effect of bleaching on tooth color but a few have evaluated the behavior of other optical properties, including fluorescence …”

Section: Introductionmentioning

confidence: 99%

“…9 The peroxides used for tooth whitening not only oxidizes the stain molecule into colorless compounds, it also alters the tooth structure surface which in result reflects the light differently. 10 Most studies on the optical properties of teeth have focused only on the effect of bleaching on tooth color [11][12][13] but a few have evaluated the behavior of other optical properties, including fluorescence. 14,15 Fluorescence is a form of luminescence that consists of the rapid emission of light by fluorophores whose electronic states were excited by absorption of light.…”

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confidence: 99%

Whitening‐dependent changes of fluorescence of extracted human teeth

Sanchez

Aleksić

Dramićanin

et al. 2017

J Esthet Restor Dent

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The appearance of human teeth and dental materials and their changes upon aging and exposure to different agents (staining, whitening) is a topic of great relevance to esthetic dentistry. While some appearance parameters, such as color, translucency, and gloss, have been thoroughly studied, fluorescence and its influence on overall tooth appearance is still not well understood, yet it has influenced the development of fluorescence emitting restorative materials.

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“…2 Revisão de Literatura A odontologia estética vem crescendo a cada dia e se tornando um fator primordial para os pacientes, assim nota-se que os clínicos estão bem conscientes da importância do clareamento dental na prática clínica diária, principalmente por ser uma abordagem segura e conservadora (LUQUE-MARTINEZ et al, 2016).…”

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Alterações morfológicas e químicas do esmalte humano após o clareamento dental: avaliação <i>in situ</i>

Soares¹

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elementos, o grupo LPF35HL obteve o menor valor de cálcio (Ca), possuindo diferença estatisticamente significante quando comparado com o grupo EXP10LHV, enquanto os valores de fosfato (P) permaneceram constantes. Morfologicamente somente o grupo EXP10LHV demostrou maior planificação da superfície quando comparado o período de 7 dias com 15 dias. Conclusão: Os diferentes protocolos clareadores empregados, demonstraram alterações pontuais na variação dos elementos químicos e na morfologia do esmalte dental ao longo do período de avaliação. Palavras-chave: Espectrometria. Fotoclareamento. Nanotecnologia. ABSTRACT Morphological and chemical changes of human enamel after tooth bleaching: in situ evaluation Introduction: The tooth color change is one of the factors that contributes most to the smile imbalance, and dental bleaching is widely diffused and requested by the patients. Objective: The aimed of this in situ study is to evaluate the morphological and chemical changes of the enamel when submitted to three activated hydrogen peroxide bleaching agents with hybrid light source and a placebo agent (gel without hydrogen peroxide), using energy-dispersive X-ray spectroscopy (EDS). Methodology: Fragments of human third molars were divided into four groups (n = 12) to perform a bleaching session with five eight minute applications of bleaching gels: Placebo (Plac); Lase Peroxide Flex 35% and 15% (DMC) (LPF35LH and LPF15LH); 10% experimental gel (DMC) (EXP10LHV), and photocatalyzed with hybrid light: blue LED / diode laser (LH) (Whitening Lase II, DMC) or violet LED / diode laser (LHV). After bleaching, the specimens were fixed to intraoral devices used by participants for 15 days. The inorganic composition and topography of the enamel surface were analyzed before and after bleaching, and after 3, 7 and 15 days of exposure to saliva. The elementary values of the composition were analyzed by one-way ANOVA at a repeated measures and Tukey's test. For the topography the scores were determined by three examiners previously calibrated by the Kappa test and the Friedman and Kruskal-Wallis statistical test were applied, and the individual comparisons were performed by the Dunn test (α = 0.05). Results: In general, therewere no significant changes in the elemental percentage of enamel in the different periods studied. When analyzing the two main elements, the LPF35HL group had the lowest calcium (Ca) value, which had a statistically significant difference when compared to the EXP10LHV group, while the phosphate (P) values remained constant. Morphologically, only the EXP10LHV group showed greater surface planning when compared to the period of 7 days with 15 days. Conclusion: The different bleaching protocols employed showed specific alterations in the variation of the chemical elements and the morphology of the dental enamel during the evaluation period.

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Comparison of efficacy of tray-delivered carbamide and hydrogen peroxide for at-home bleaching: a systematic review and meta-analysis

Abstract: Tray-delivered CP gels have a slightly better whitening efficacy than HP-based products in terms of ΔE. This should be interpreted with caution as the data of ΔSGU did not show statistical difference between the products.

Cited by 86 publications

References 48 publications

Effect of temperature and storage time on dental bleaching effectiveness

Effect of temperature and storage time on dental bleaching effectiveness

Whitening‐dependent changes of fluorescence of extracted human teeth

Alterações morfológicas e químicas do esmalte humano após o clareamento dental: avaliação <i>in situ</i>

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