Comparison of echo-enhanced ultrasound with fluoroscopic MCU for the detection of vesicoureteral reflux in neonates

Abstract

The role of echo-enhanced sonography is limited at present in our neonatal population as a screening examination. Its ability to detect cases of high-grade reflux may make it an attractive alternative in follow-up of known cases of VUR, and may help to reduce radiation exposure in this group.

Contrast-enhanced Sonographic Detection of Vesicoureteral Reflux in Children: Comparison with Voiding Cystourethrography

“…There are studies using it in children as well [10 -13, 16, 17]. Comparative studies between VCUG and CES showed satisfactory results, with sensitivity between 70 % and 100 % and specificity between 86 % and 97 % [12,13,16,18]. The results of our study with sensitivity of 96 %, specificity of 94.8 % and negative predictive value of 99.2 % provide supportive evidence for the role of CES in the diagnosis of VUR.…”

Echo-enhanced voiding urosonography for detection of vesicoureteric reflux in children

“…The group from Heidelberg found excellent sensitivity (100%) of EEVUS compared with VCUG for detection of VUR when harmonic options were used [4,5]. Similar to us [3], McEwing et al [1] and Kenda et al [2] used only conventional US imaging and this was probably the reason for low sensitivity in the three studies. Although McEwing et al [1] performed urosonography in a cyclic manner, the sensitivity for VUR detection in their study was still low.…”

“…Similar to us [3], McEwing et al [1] and Kenda et al [2] used only conventional US imaging and this was probably the reason for low sensitivity in the three studies. Although McEwing et al [1] performed urosonography in a cyclic manner, the sensitivity for VUR detection in their study was still low. Recently, we recommenced investigation of children with UTI with EEVUS, using US devices with harmonic tissue imaging.…”

“…We read with great interest the paper by McEwing et al [1] on the use of echo-enhanced sonography for detection of vesicoureteric reflux (VUR) in a selected group of children, and we would like to comment briefly on the methodology and results that we have obtained with this new and attractive technique.…”

Nonionizing photoacoustic cystography in vivo

“…Echo-enhanced urosonography has been applied to monitor VUR, and it offers the advantages of nonionizing, real-time, and portable imaging capability [14]. However, echoenhanced urosonography is sensitive to high-grade reflux only [16]. Therefore, US imaging alone cannot be used for VUR tracking.…”