1964
DOI: 10.1136/sti.40.2.122
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Comparison of Different Antibiotics in the Treatment of Acute Gonorrhoea in African Negroes

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“…In West Africa, although 99 % of 74 gonococcal strains were found to be 'fully sensitive ' in 1961(World Health Organisation, 1963, Clarke (1964) working in Lagos, encountered treatment failure in 21-4 % of patients who received procaine penicillin 2-4 megaunits daily for three consecutive days although no sensitivity tests were performed. In Yaunde, Cameroons, Millan and Huet (1970), using a disc diffusion method, reported that 10 of their 18 gonococcal strains were 'sensitive' in penicillin.…”
Section: Resultsmentioning
confidence: 99%
“…In West Africa, although 99 % of 74 gonococcal strains were found to be 'fully sensitive ' in 1961(World Health Organisation, 1963, Clarke (1964) working in Lagos, encountered treatment failure in 21-4 % of patients who received procaine penicillin 2-4 megaunits daily for three consecutive days although no sensitivity tests were performed. In Yaunde, Cameroons, Millan and Huet (1970), using a disc diffusion method, reported that 10 of their 18 gonococcal strains were 'sensitive' in penicillin.…”
Section: Resultsmentioning
confidence: 99%
“…Less favourable results, in areas where results with all antibiotics are less impressive (Willcox, 1970) , have been reported by Clarke (1964) in a comparative study in Nigeria involving 462 African males with acute gonorrhoea. A cure rate of 77.7 % was achieved with spectinomycin (1 .6 g), compared with 66.6 % with procaine penicillin (2.4 mega units) and 82.2 % with a single 2.5 g dose of spiramycin.…”
Section: Therapeutic Trialsmentioning
confidence: 91%