Comparison of clinical outcomes of adenocarcinoma and adenosquamous carcinoma in uterine cervical cancer patients receiving surgical resection followed by radiotherapy: A multicenter retrospective study (KROG 13-10)

The pretreatment neutrophil-to-lymphocyte ratio predicts therapeutic response to radiation therapy and concurrent chemoradiation therapy in uterine cervical cancer

“…Previous studies [14,15] have shown that FIGO stage, Hb level, and tumor size are significant prognostic factors of cervical cancer and the results of the present study were compatible as shown in Table 1. In addition, treatment modality (CCRT vs. RT) was also reported to be an impact prognostic factor, as CCRT had a higher rate of success than RT alone [12].…”

Comparison of adenocarcinoma (ACA) and squamous cell carcinoma (SCC) of the uterine cervix in a sub-optimally screened cohort: A population-based epidemiologic study of 51,842 women in Brazil

“…Whereas several studies have demonstrated that patients with ACA have poorer prognosis than those with SCC [3][4][5][6][7][8][9][10]27,28,32] this study shows no difference in the therapeutic response and death rate at the end of the first course of cancer-directed therapy, which is in accordance with the findings of other studies that indicates similar recurrence rate [33][34] and survival [4,5,35] between both histologic types of cervical cancer. Considering patients with locally advanced and advanced disease, FIGO stage ≥ IIB, radiotherapy alone was the treatment strategy for 43.9% of the ACA patients and 52% of the SCC patients, and an inadequate response was observed in 33.3% and 31.6% of them, respectively.…”

Prognostic factors and adjuvant therapy on survival in early-stage cervical adenocarcinoma/adenosquamous carcinoma after primary radical surgery: A Taiwanese Gynecologic Oncology Group (TGOG) study

“…Baek et al (n ¼ 337) observed no differences in patterns of recurrence, time to recurrence, RFS, and OS between AC and ASC [22]. A Korean multicenter retrospective study (total n ¼ 1323; AC/ASC, n ¼ 255) reported that AC histology was associated with poor survival outcomes than SCC, and prognosis of ASC histology was closer to that of SCC histology [23]. Conversely, a meta-analysis reported that ASC may have poorer outcomes compared with AC of the cervix [24].…”