Comparison of Clinical Effects of Dexketoprofen and Paracetamol Used for Analgesia in Endoscopic Retrograde Cholangiopancreatography

Akinci, Nuran; Bakan, Nurten; Karaören, Gülşah; Tomruk, Şenay Göksu; Sökmen, H. Mehmet; Yanli, Yonca; Akçay, Mehmet Erdem

doi:10.5152/tjar.2016.09483

Cited by 8 publications

(1 citation statement)

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“…Postoperative pupillary center displacement is considered for two reasons: Firstly, pupils constrict due to the anti-mydriatic effect of brimonidine, which conduct to slight displacement of pupil center. Studies have found a correlation between pupillary excursion (the distance from the center of the pupil to the center of the cornea) and dark pupil diameter, which increases pupillary excursion when pupil diameter is increased by changing lighting conditions from photopic to mesopic, the displacement increased with the pupil diameter of the subjects ( 24 , 25 ). The second reason is that vault changes with the pupil, which has certain mechanical stimulation to the iris tissue, resulting in subtle changes in the pupil center.…”

Section: Discussionmentioning

confidence: 99%

Effects of brimonidine tartrate 0.2 and 0.15% ophthalmic solution on the static and dynamic pupil characteristics

et al. 2023

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AimsTo investigate the differences between 0.2 and 0.15% brimonidine tartrate eye drops for anti-mydriatic effects and the optical quality under different light conditions.MethodsThis prospective study involved 80 consecutive high myopia patients undergoing implantation of a V4c ICL. The patients were randomly instilled with brimonidine 0.2 and 0.15% 2 weeks postoperatively. Visual quality, pupil center, pupil size, and refraction under different light conditions were measured before and 0.5 h after brimonidine administration. A symptom questionnaire was also evaluated.ResultsThere was no statistical difference in the static and dynamic pupil diameters and velocity after LS between the two groups (p > 0.05). The 0.2% group had significant changes in pupil center before and after treatment, while there was no obvious movement of the 0.15% group under all illumination condition (p > 0.05). The OSI after treatment of the 0.15% group was lower than that of 0.2% group (p = 0.012). The PVA9% and PVA100% of the 0.15% group was higher than that of 0.2% group in the dark (p = 0.009, p = 0.012). The HOA RMS of the 0.15% group was lower than that of 0.2% group (p = 0.016). The QIRC score in the 0.15% group was significantly higher than that in the 0.2% group (p = 0.043).Conclusion0.15 and 0.2% brimonidine tartrate eye drops had similar anti-mydriatic ability, while 0.15% group had better visual quality than 0.2% concentration, and hardly introduced pupil shift. 0.15% brimonidine tartrate eye drops may be more suitable for patients with nocturnal glare symptoms in the early postoperative period after ICL implantation.

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Section: Discussionmentioning

confidence: 99%