Comparison of cerebral tissue oxygenation values in full term and preterm newborns by the simultaneous use of two near-infrared spectroscopy devices: an absolute and a relative trending oximeter

Abstract

The aim of this study is to compare a two-wavelength light emitting diode-based tissue oximeter (INVOS), which is designed to show trends in tissue oxygenation, with a four-wavelength laser-based oximeter (FORE-SIGHT), designed to deliver absolute values of tissue oxygenation. Simultaneous values of cerebral tissue oxygenation (StO2) are measured using both devices in 15 term and 15 preterm clinically stable newborns on the first and third day of life. Values are recorded simultaneously in two periods between which oximeter sensor positions are switched to the contralateral side. Agreement between StO2 values before and after the change of sensor position is analyzed. We find that mean cerebral StO2 values are similar between devices for term and preterm babies, but INVOS shows StO2 values spread over a wider range, with wider standard deviations than shown by the FORE-SIGHT. There is relatively good agreement with a bias up to 3.5% and limits of agreement up to 11.8%. Measurements from each side of the forehead show better repeatability for the FORE-SIGHT monitor. We conclude that performance of the two devices is probably acceptable for clinical purposes. Both performed sufficiently well, but the use of FORE-SIGHT may be associated with tighter range and better repeatability of data.

10 cm H2O PEEP application in laparoscopic surgery and cerebral oxygenation: a comparative study with INVOS and FORESIGHT

“…The difference between precision levels of the devices was argued to be caused by the differences between measurement algorithms, laser technology, and penetration of light at different wavelengths, sensitivity of the detectors, and interference between the devices that were used simultaneously. Szczapa et al [25] conclude that performance of the two devices is probably acceptable for clinical purposes. Both performed sufficiently well, but the use of FORESIGHT may be associated with tighter range and better repeatability of data.…”

Comparison of tissue oximeters on a liquid phantom with adjustable optical properties

“…Since there is no simple test so far and the specific StO 2 value depends on several assumptions, it is not surprising that oximeters from different manufacturers provide different StO 2 values as established by numerous studies [7,[11][12][13][14][15][16][17][18]. With the lack of a standard, the need arose to translate between different oximeters within and between trials (e.g.…”

Cerebral oximetry in preterm infants: an agenda for research with a clear clinical goal

“…36,39,40 Third, even devices that agree within the normal range may deviate significantly in the hypoxic range as shown in infants born at term. 41 This is most important, since it is in the hypoxic range that values may-or may not-lead to change in clinical care.…”