“…It was our contention that in those studies that reported impaired active-avoidance behavior following damage of the caudate nuc1eus, lesions were directed at the postero-ventral portions of the structure or were so large that they seriously infringed on these areas. Localized lesions directed at the antero-dorsal portions of the caudate nucleus do not typically result in this type of impairment, and the studies cited by Kirkby bear tbis out (Fox, Kimble, & Lickey, 1964;Albert & Bignami, 1968;Winocur & Mills, 1969). On the other hand, Thompson and his collaborators (1958Thompson and his collaborators ( , 1959Thompson and his collaborators ( , 1963, Green, Beatty, &Schwartzbaum (1967), andRomanovskaya (1957), who are cited as having reported deficits in conditioned-avoidance behavior, consistently destroyed postero-ventral tissue, wbich, in the ~ases of Thompson and Romanovskaya, was also accompanied by extensive damage to other parts of the caudate nuc1eus.…”