Comparison of blood flow assessment between laser doppler velocimetry and the hydrogen gas clearance method in ischemic intestine in dogs

Oohata, Yoshihiro; Mibu, Ryuichi; Hotokezaka, Masayuki; Ikeda, Shin‐ichi; Nakahara, Shosaku; Itoh, Hideaki

doi:10.1016/s0002-9610(05)81017-7

Cited by 16 publications

(11 citation statements)

References 11 publications

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“…Hydrogen gas clearance Hydrogen gas clearance was attempted for intestinal microcirculation assessment in earlier experimental studies [36,37,38] . The basic paradigm of hydrogen clearance consists of inserting a positively polarized electrode into tissue, administering H2 either by respiration or intra-arterially, allowing the H2 to be cleared from arterial blood, and then monitoring the exponential clearance rate of H2 from the tissue [39] .…”

Section: Doppler Ultrasoundmentioning

confidence: 99%

How to assess intestinal viability during surgery: A review of techniques

Urbanavičius

Pattyn²,

Putte³

et al. 2011

WJGS

188

156

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Objective and quantitative intraoperative methods of bowel viability assessment are essential in gastrointestinal surgery. Exact determination of the borderline of the viable bowel with the help of an objective test could result in a decrease of postoperative ischemic complications. An accurate, reproducible and cost effective method is desirable in every operating theater dealing with abdominal operations. Numerous techniques assessing various parameters of intestinal viability are described by the studies. However, there is no consensus about their clinical use. To evaluate the available methods, a systematic search of the English literature was performed. Virtues and drawbacks of the techniques and possibilities of clinical application are reviewed. Valuable parameters related to postoperative intestinal anastomotic or stoma complications are analyzed. Important issues in the measurement and interpretation of bowel viability are discussed. To date, only a few methods are applicable in surgical practice.Further studies are needed to determine the limiting values of intestinal tissue oxygenation and flow indicative of ischemic complications and to standardize the methods.

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Section: Doppler Ultrasoundmentioning

confidence: 99%

How to assess intestinal viability during surgery: A review of techniques

Urbanavičius

Pattyn²,

Putte³

et al. 2011

WJGS

188

156

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“…Therefore, any method for evaluation of intestinal viability based on intestinal blood flow should use direct evaluation of blood flow in the mucosal and submucosal layers. Ahn et al 10 , using laser Doppler flowmetry, and Oohata et al 2 , by hydrogen gas clearance, showed a strong correlation between submucosal and subserosal blood flow. Therefore, evaluation of blood flow in the subserosa by CCD microscopy in the present study may reflect blood flow in the intestinal tissues, thereby enabling intraoperative intestinal viability to be estimated by a less invasive.…”

Section: Discussionmentioning

confidence: 97%

“…However, fluorescein assessment lacks precision and sufficient objectivity, as it is based on a macroscopic impression of the intestinal microcirculation. On the other hand, Doppler methods, which involve quantitative evaluation of microcirculatory blood flow, have the disadvantage of being vulnerable to other signals at some sites of measurement -in the large vessels, for instance -and thus fail to determine tissue blood flow precisely 2,10 .…”

Section: Discussionmentioning

confidence: 99%

Experimental model to estimate intestinal viability using charge-coupled device microscopy

Yasumura

Mori

Takagi

et al. 2003

British Journal of Surgery

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“…Second, constant contact between the probe and the tissue surface must be maintained without producing tissue compression, since compression was found to induce local ischemia and reduce flux values significantly. 15 Third, continuous measurement of the serosal blood flow is difficult because motion artifacts can occur, and obtaining a stable recording without any simultaneous manipulation requires several minutes. In contrast, endoscopic LDF measurements of mucosal blood flow in the sigmoid colon can be obtained with moderate air insufflation, without stretching the mucosal folds.…”

Section: Discussionmentioning

confidence: 99%