Comparison of Autologous Serum and Umbilical Cord Serum Eye Drops for Dry Eye Syndrome

Yoon, Kyung-Chul; Heo, Hwan; Im, Seong-Kyu; You, In Cheon; Kim, Yoon-Ha; Park, Yeoung-Geol

doi:10.1016/j.ajo.2007.03.016

Cited by 125 publications

(112 citation statements)

References 26 publications

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“…Human tears contain a protein array that is similar to serum but is lacking lactoferrin, lysozyme and tear-specific prealbumin [25]. Yoon et al [26] reported the use of diluted antilogous serum as eye drops for severely diseased patients. In their studies, they diluted the serum 1:20 with saline, and did not add any of the tear-specific proteins.…”

Section: Discussionmentioning

confidence: 99%

Friction Measurements on Contact Lenses in Their Operating Environment

et al. 2011

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An important issue concerning the use of soft contact lenses is comfort, which, among other factors, has been related to the level of friction between the anterior side of the lens and the inner eyelid. Although several studies have been carried out to investigate the frictional properties of contact lenses, these have not taken the physiological environment of the eye into account. In use, lenses are in contact with proteins present in tears, with corneal cells and with the palpebral conjunctiva (clear membrane on inner eyelid). The focus of this study was to establish a biologically relevant measurement protocol for the investigation of friction of contact lenses that would mimic the eye's physiological environment. By optimizing parameters such as the composition of the friction counter surface, the lubricant solution, the normal load and the velocity, an ideal protocol and setup for microtribological testing could be established and used to perform a comparative study of various commercially available soft contact lenses.

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Section: Discussionmentioning

confidence: 99%

Friction Measurements on Contact Lenses in Their Operating Environment

et al. 2011

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“…Both autologous serum and umbilical cord serum owe their efficacy to the presence of various growth factors, like EGF, acidic and FGF, PDGF, hepatocyte growth factor, vitamin A, transforming growth factor (TGF)-␤, substance P, insulin-like growth factor (IGF)-1, nerve growth factor (NGF), fibronectin, and serum antiproteases, such as ␣2-macroglobulin [19][20][21]. The concentrations of EGF, TGF-␤, and NGF are several times higher in umbilical cord serum than peripheral blood serum [22,23].…”

Section: Article In Pressmentioning

confidence: 99%

“…Recently, the use of UCS in the form of eyedrops has been reported as a new treatment for severe ocular surface disorders [20,21]. UCS contains many growth factors, such as EGF, TGF-␤, IGF-1, and NGF [22].…”

Section: Article In Pressmentioning

confidence: 99%

Regeneration of chronic tympanic membrane perforation using 3D collagen with topical umbilical cord serum

Jang

Cho

Yeo

et al. 2013

International Journal of Biological Macromolecules

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“…BUT and Schirmer test were performed as previously described. 20 Keratoepitheliopathy was scored by multiplying the area score (0-3) by the density score (0-3) after staining with 1% fluorescein dye. 21 Subjective symptoms such as burning, dryness, and foreign body sensation were graded on a numerical score of 0 to 4, with 0 representing no symptom and 4 representing very severe symptoms that caused discomfort and interfered with normal activities.…”

Section: Postoperative Treatmentmentioning

confidence: 99%