Comparison of Antioxidant Activities of Isoflavones from Kudzu Root (<i>Pueraria lobata</i> Ohwi)

Jun, Mira; Fu, Hsueh; Hong, Jongki; Wan, Xiaochun; Yang, Chen; Ho, Chi‐Tang

doi:10.1111/j.1365-2621.2003.tb07029.x

Cited by 169 publications

(114 citation statements)

References 34 publications

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“…For more detail can be seen in the Table 3. Table 3: Power levels of antioxidant by DPPH method [18].…”

Section: Resultsmentioning

confidence: 99%

Antioxidant Activity of Methanol Extract/Fractions of Senggani Leaves (Melastoma candidum D. Don)

Mr¹,

Zulfisa²

2017

Pharm Anal Acta

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Senggani (Melastoma candidum D. Don) leafis one of many plants in hilly areas around the city of Bukittinggi and one of biological potencies that can be utilized primarily as antioxidant and used to treat various diseases. Some active compounds in Melastoma genus that has activity as an antioxidant such as flavonoids and tannins.This study aims to examine the activity of free radical scavenging by methanol extract of senggani leaves and their fractions. The antioxidant activity of methanol extract of senggani leaves and its fractions was evaluated in vitro assays using the 2,2-diphenyl-1-picrilhidrazine (DPPH) method. The amount of antioxidant activity is characterized by the value of IC50 which is concentration of extract and fractions required to inhibit 50% of DPPH free radicals. The results showed that the antioxidant activity of senggani leaves were very strong for ethyl acetate and chloroform fractions with IC50 valuesof 43,1301 μg/ml and 43,8924 μg/ml, respectively, while for methanol fraction was strong with IC50 value of 65,6521 μg/ml. While the fraction of n hexane was categorized moderate with IC50 value of 122,3880 μg/ml. Senggani leaves have potential to be used as natural antioxidant in preventing free radicals.

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“…For more detail can be seen in the Table 3. Table 3: Power levels of antioxidant by DPPH method [18].…”

Section: Resultsmentioning

confidence: 99%

Antioxidant Activity of Methanol Extract/Fractions of Senggani Leaves (Melastoma candidum D. Don)

Mr¹,

Zulfisa²

2017

Pharm Anal Acta

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“…The strength of the antioxidant activity was determined based on IC 50 value, referring to Jun et al (2003) where the value of < 50 ppm is considered as strong, 50-100 ppm as active, 100-250 ppm as moderate, 250-500 ppm as weak, and > 500 ppm as inactive.…”

Section: Resultsmentioning

confidence: 99%

Phytochemical Screening and Antioxidant Activity of Selekop (Lepisanthes amoena) Fruit

et al. 2017

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Selekop (Lepisanthes amoena (Hassk.) Leenh.) plant leaves are used by the Dayak tribe of East Kalimantan as traditional cosmetics. Selekop fruit is also edible, but not well known. This study was conducted to obtain the phytochemical content and antioxidant assay in flesh, seed and pericarp extracts from the fruit of Selekop. Phytochemical analysis was conducted on ethanol extract for identification of flavonoid, alkaloid, tannin, saponin, triterpenoid and steroid. The antioxidant activity was done by DPPH assay with ascorbic acid as positive control. The flesh contained flavonoid, saponin, and tannin; the seed contained flavonoid, alkaloid, saponin, triterpenoid, and tannin; and the pericarp contained flavonoid, alkaloid, saponin, triterpenoid, and tannin. Analysis of antioxidant activity revealed the following Inhibitory Concentration (IC 50 values): 122.51 ppm of flesh, 63.30 ppm of seed, 53.21 ppm of pericarp and 3.06 ppm of ascorbic acid. Based on these results, the ethanol extract of the seed and the flesh had a phytochemical content and antioxidant activity which was better than the flesh extract from Selekop fuit.

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“…The test compounds could be categorized according to the strength of the antioxidant into groups of various intensity according to the IC 50 value. Antioxidant activity with an IC 50 value of less than 50 ppm was categorized as very strong, strong if the IC 50 value was between 50 and 100 ppm, moderate if the value of the IC 50 was 101-250 ppm, and weak if the IC 50 value was greater than 500 ppm [21].…”

Section: Antioxidant Activity Test By Quantitative Methods Of Dpphmentioning

confidence: 99%

Tyrosinase Inhibition, 2,2-Diphenyl-1-Picrylhydrazyl Radical Scavenging Activity, and Phytochemical Screening of Fractions and Ethanol Extract From Leaves and Stem Bark of Matoa (Pometia Pinnata)

Sauriasari

Azizah

Basah

2017

Asian J Pharm Clin Res

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Objective: This study aims to investigate the potency of matoa as a tyrosinase inhibitor and antioxidant and also to identify the chemical compounds in the most active fraction and an ethanol extract from the leaves and stem bark of matoa.Methods: The extracts were tested for their tyrosinase inhibitory activity by evaluating the formation of L-dopachrome at 490 nm. Antioxidant activity was tested using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method. The most active extract from liquid-liquid partition analysis was fractionated, and then, the assays were performed. Results:The ethanol extract of leaves and stem bark of matoa showed weak anti-tyrosinase activity (percent inhibition was 24.54±0.22% and 21.93±0.57%, respectively, final concentration 200 μg/mL), but they showed strong DPPH radical scavenging activity (IC 50 values were 6.11 μg/mL and 5.47 μg/mL, respectively). The ethyl acetate fraction was the most active fraction with an IC 50 value of 5.38 μg/mL. Ethanol extract from the leaves and stem bark of matoa and the ethyl acetate fraction contains flavonoids, tannins, saponins, triterpenoids, and glycosides. Conclusion:Matoa does not have potency as a tyrosinase inhibitor, but it has good antioxidant activity, although still lower than that of quercetin.

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Comparison of Antioxidant Activities of Isoflavones from Kudzu Root (Pueraria lobata Ohwi)

Cited by 169 publications

References 34 publications

Antioxidant Activity of Methanol Extract/Fractions of Senggani Leaves (Melastoma candidum D. Don)

Antioxidant Activity of Methanol Extract/Fractions of Senggani Leaves (Melastoma candidum D. Don)

Phytochemical Screening and Antioxidant Activity of Selekop (Lepisanthes amoena) Fruit

Tyrosinase Inhibition, 2,2-Diphenyl-1-Picrylhydrazyl Radical Scavenging Activity, and Phytochemical Screening of Fractions and Ethanol Extract From Leaves and Stem Bark of Matoa (Pometia Pinnata)

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