Comparison of 50 kV Facilities for Contact Radiotherapy

Fletcher, C L; Mills, John A.; Baugh, Gareth; Roughton, J.

doi:10.1016/j.clon.2007.07.005

Cited by 7 publications

(5 citation statements)

References 13 publications

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“…It has been used in many reported studies to investigate dose distributions for small stereotactic fields, 1-5 photon beam relative dosimetry, 6,7 and IMRT-QA. 8,9 Additionally, because of the reported energy independence, [10][11][12] it has found applications in low energy brachytherapy 13 and orthovoltage dosimetry, [14][15][16] and more recently, to quantify output, dose profiles, and depth dose for small ͑down to 1 mm͒ orthovoltage ͑40-225 kVp͒ fields for use in translational studies. 17,18 However, whereas reports published in 2005 and 2006 have shown at most weak ͑Ͻ10%͒ dependencies of response on energy, 10-12 more recent publications and measurements at our institution have indicated stronger ͑Ͼ20%͒ dependencies on energy, [19][20][21][22] which seems to be in direct contradiction.…”

Section: Introductionmentioning

confidence: 99%

Investigation of energy dependence of EBT and EBT‐2 Gafchromic film

et al. 2010

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The results of this study indicated that differences in energy response of EBT and EBT-2 films were due to differences in the chemical composition and therefore the effective atomic number of the film, which have changed over time. To achieve an energy independent dosimeter over a range of kilovoltage energies, the effective atomic number of the dosimeter must be closely matched to that of water. Small deviations in chemical composition can lead to large deviations in response as a function of energy.

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Section: Introductionmentioning

confidence: 99%

Investigation of energy dependence of EBT and EBT‐2 Gafchromic film

et al. 2010

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“…They tested the machine for single runs over 100 h. After a final tuning of the tube, it was found to be fully satisfactory, with a variation of less than 2% over such a long period of time. All these physical characteristics are of major importance to plan the proper treatment of a rectal cancer and to compare the performance of the beam of the Papillon 50 to other 50-kV machines [14,15]. These parameters change with the type of rectal applicators used.…”

Section: Stability Of the Beammentioning

confidence: 98%

Renaissance of contact x-ray therapy for treating rectal cancer

Gérard

Myint

Croce

et al. 2011

Expert Review of Medical Devices

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Contact x-ray therapy (CXRT) with 50 kV has proven to be an efficient radiation therapy technique to achieve local control and rectal preservation for early rectal adenocarcinoma. Despite these results, CXRT has not been used due to the shortage of the no longer manufactured Philips RT 50™ unit. Recently, a new CXRT machine (Papillon 50™) became available on the market. This machine delivers a beam of 50 kV with a dose rate close to 15 Gy/min and has a percentage depth dose of 50% at 6-7 mm. The applicator size varies from 2-3 cm in diameter. Due to the original design of the main tube, treatment delivery is quick and more comfortable for the patients. An online viewing system incorporated in the tube allows a good visualization of the tumor with improved accuracy of radiation delivery. An international collaborative trial (Contact Endoscopic Microsurgery [CONTEM]) was set up to accrue approximately 300 cases of rectal adenocarcinoma staged T1, T2 or early T3 tumors in the UK, France, Denmark and Sweden. This trial should confirm the role of CXRT in curative treatment with organ preservation for early rectal cancers.

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“…The dose is prescribed at the applicator surface. The dose falls off rapidly and is approximately 60% at 0.5 cm and 40% at 1 cm (with slight variation according to applicator size) [27] , [28] . Exophytic tumour which extends inside the applicator will receive a proportionally higher dose, this is difficult to quantify due to the steep dose gradient close to the X-Ray target.…”

Section: Timing Of Cxb Treatmentmentioning

confidence: 99%

GEC ESTRO ACROP consensus recommendations for contact brachytherapy for rectal cancer

Stewart

Limbergen

Gérard

et al. 2022

Clinical and Translational Radiation Oncology

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Comparison of 50 kV Facilities for Contact Radiotherapy

Cited by 7 publications

References 13 publications

Investigation of energy dependence of EBT and EBT‐2 Gafchromic film

Investigation of energy dependence of EBT and EBT‐2 Gafchromic film

Renaissance of contact x-ray therapy for treating rectal cancer

GEC ESTRO ACROP consensus recommendations for contact brachytherapy for rectal cancer

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