Comparison of 3% saline and 0.9% normal saline nebulization as diluent in children with bronchiolitis

Sapkota, Shobha; Kaleem, Ammara; Huma, Suffura; Ud-Din, Muhammad Aleem; Ahmad, Shabbir; Alam, Sobia Shah

doi:10.47391/jpma.569

Cited by 3 publications

(1 citation statement)

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“…Agen mukoaktif lainnya adalah ekspetoran yang memiliki cara kerja membasahi sputum dan saluran napas sehingga tidak dehidrasi yang memungkinkan sputum melekat dan susah dikeluarkan oleh refleks batuk (Wibowo, 2021). Hipertonik salin juga memiliki kemiripan mekanisme kerja seperti ekspetoran yaitu melembabkan saluran pernapasan sehingga sputum lebih mudah dikeluarkan (Sapkota et al, 2021). Kemiripan dengan mekanisme kerja lainnya adalah sebagai mukokinetik dengan cara meningkatkan gerakan silia pada saluran pernapasan (Wibowo, 2021).…”

Section: Kajian Pustakaunclassified

Penggunaan NaCl 3% sebagai Terapi Inhalasi pada Balita dengan Bronkopneumonia: Studi Kasus

Baeti,

Mardhiyah

2023

Mal Health Stu J.

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Bronchopneumonia is a respiratory problem that affects toddlers. This is caused by bacteria, viruses, fungi, chemicals exposure, and lung structural damage. This infectious disease has impacts on growth and development and mortality in children. This research aims to describe nursing care related to ineffective airway clearance using hypertonic saline (HS) 3% NaCl as inhalation therapy in toddlers with bronchopneumonia. This research design used a descriptive method with a case study approach. Data collection was obtained through interviews with the client's family and 3 days observation and physical assessment to client. The instrument used was a patient assessment instrument from Hospital, SDKI, SLKI, and SIKI. The results of this research stated that the utilization of HS was effective in reducing the severity of bronchopneumonia symptoms such as increasing airway clearance and increasing oxygen saturation. HS was thinning phlegm and increasing cough reflex in toddlers. This is due to the hypertonic action mechanism, which disrupts sputum ion bonds which can reduce the binding and cross-linking in it, moisten the respiratory tract, and stimulate the release of prostaglandin E2 so the cilia move faster and stimulate the cough reflex. Keywords: 3% Nacl, Bronchopneumonia, Hypertonic Saline, Inhalation Therapy, Mucoactive Agent, Toddlers ABSTRAK Bronkopneumonia adalah salah satu masalah pernapasan yang banyak menjangkit balita. Hal ini diakibatkan oleh bakteri, jamur, virus, kerusakan stuktur paru-paru, dan pajanan bahan kimia. Penyakit infeksi ini berdampak pada tumbuh kembang dan angka kematian pada anak. Penelitian ini bertujuan untuk mendeskripsikan asuhan keperawatan terkait bersihan jalan tidak efektif menggunakan cairan hipertonik salin berupa NaCl 3% sebagai terapi inhalasi pada balita dengan bronkopneumonia. Desain penelitian ini menggunakan metode deskriptif dengan pendekatan studi kasus. Pengambilan data diperoleh melalui wawancara pada keluarga klien dan observasi serta pemeriksaan fisik pada klien selama 3 hari. Instrumen yang digunakan adalah instrumen pengkajian pasien dari rumah sakit, SDKI, SLKI, dan SIKI. Hasil dari penelitian ini menyatakan bahwa penggunaan hipertonik salin NaCl 3% efektif dalam menurunkan keparahan gejala dari bronkopneumonia seperti meningkatkan clearence jalan napas dan meningkatkan saturasi oksigen. NaCl 3% mengencerkan dahak dan meningkatkan refleks batuk pada balita. Hal ini disebabkan karena mekanisme kerja hipertonik yaitu mengganggu ikatan ion sputum yang dapat mengurangi keterikatan dan ikatan silang yang ada di dalamnya, melembabkan saluran pernapasan, serta merangsang pelepasan prostaglandin E2 sehingga gerakan silia lebih cepat dan merangsang reflek batuk. Kata Kunci: Agen Mukoaktif, Balita, Bronkopneumonia, Hipertonik Salin, Nacl 3%, Terapi Inhalasi

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Section: Kajian Pustakaunclassified

Penggunaan NaCl 3% sebagai Terapi Inhalasi pada Balita dengan Bronkopneumonia: Studi Kasus

Baeti,

Mardhiyah

2023

Mal Health Stu J.

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Nebulised hypertonic saline solution for acute bronchiolitis in infants

Zhang

Mendoza-Sassi

Wainwright

et al. 2023

Cochrane Database of Systematic Reviews

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A modern view on the treatment of acute bronchiolitis in pediatric intensive care units: a review

Tsygankov¹,

Ovsyannikov

Афуков

et al. 2022

Annals of Critical Care

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INTRODUCTION. The literature has accumulated enough data on the treatment of children with acute bronchiolitis (OB). However, this information is formed mainly on the general population of patients with OB and is often not applicable to patients with a severe course of the disease. From the standpoint of evidence-based medicine, routine use of medications is not recommended in modern consent documents, and there are also no clear recommendations on respiratory support and certain aspects of intensive care in children with OB. OBJECTIVES. To analyze approaches to therapy in children with severe acute course in need of intensive care, and to assess the validity, effectiveness and safety of the use of the analyzed groups of drugs and respiratory strategies. MATERIALS AND METHODS. The analysis of publications in the electronic databases PubMed and the Russian Scientific Citation Index on the keywords “bronchiolitis”, “intensive care units”, “critical care”, “fluid therapy”, “respiratory therapy”, “ventilation”, “co-morbidity”; “respiratory syncytial virus”; “hypertonic saline” was carried out, “corticosteroids”; “epinephrine”; “high-flow oxygen therapy”, “inhalation”, “infant”, “bronchiolitis in children”. The date of the last search is January 15, 2022. RESULTS. This systematic review provides information on the etiology and risk factors of severe acute respiratory syndrome in children, from the standpoint of evidence-based medicine, studies on the treatment of severe acute respiratory syndrome are characterized, including in the intensive care unit with glucocorticosteroids, inhalations of bronchodilators, epinephrine, 3 % hypertonic sodium chloride solution, respiratory support, high-flow oxygenation, noninvasive ventilation, artificial ventilation, antibiotics, air-helium mixture. CONCLUSIONS. Currently, there is more information that infants with OB show a high degree of heterogeneity, while the main uncertainty lies in a misunderstanding of the processes, which patients will benefit most from a particular treatment method. Further research is needed to fill the research deficit in children with a severe course of OB.

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Comparison of 3% saline and 0.9% normal saline nebulization as diluent in children with bronchiolitis

Cited by 3 publications

References 0 publications

Penggunaan NaCl 3% sebagai Terapi Inhalasi pada Balita dengan Bronkopneumonia: Studi Kasus

Penggunaan NaCl 3% sebagai Terapi Inhalasi pada Balita dengan Bronkopneumonia: Studi Kasus

Nebulised hypertonic saline solution for acute bronchiolitis in infants

A modern view on the treatment of acute bronchiolitis in pediatric intensive care units: a review

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