2005
DOI: 10.1109/tns.2004.843154
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Comparison of 3-D OSEM versus 1-D SAGE for focal total-activity quantification in I-131 SPECT with HE collimation

Abstract: A three-dimensional (3-D) ordered-subset expectation maximization (OSEM) reconstruction algorithm used fits to the average behavior of the I-131 point-source-response function at different depths to model the detector-collimator response of a SPECT camera. The fitting function was a Gaussian, plus a single exponential to account for septal-penetration of the high-energy (HE) collimation. Results from that unregularized 3-D OSEM were compared to those with regularized one-dimensional (1-D) space-alternating gen… Show more

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Cited by 11 publications
(17 citation statements)
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“…The curve shape was that of a typical convergence, a fast increase followed by a slower approach toward an asymptote. Such convergence had been observed earlier for a 200 cm 3 sphere [6].…”
Section: Resultssupporting
confidence: 84%
“…The curve shape was that of a typical convergence, a fast increase followed by a slower approach toward an asymptote. Such convergence had been observed earlier for a 200 cm 3 sphere [6].…”
Section: Resultssupporting
confidence: 84%
“…Posttherapy SPECT projection data were corrected for dead time using a paralyzable model (13). Projection data were reconstructed with 35 iterations (6 subsets) of 3D ordered-subsets expectation maximization including triple-window–based scatter correction, CT-based attenuation correction, and compensation for depth-dependent detector response (14,15). …”
Section: Methodsmentioning
confidence: 99%
“…7). When full CDR compensation is desired, the total (i.e., including intrinsic, geometric, penetration, and scatter components) distance-dependent CDR can be determined experimentally by measuring the in-air point-source response at various distances from the collimator face (50,51) or by Monte Carlo simulations of this geometry (52). The total CDR should be determined for the radionuclide of interest, as both septal penetration and scatter are energy-dependent (in contrast to the geometric component).…”
Section: Quantitative Spect Techniques For Nonuniform Dosimetrymentioning
confidence: 99%
“…The source can then be placed on a low-scatter medium (such as a Styrofoam [The Dow Chemical Co.] cup) positioned at the required distance from the collimator. The planar acquisitions to determine CDR should be performed using a fine image matrix (512 × 512) and for at least 5 source–collimator distances in a clinically relevant range (2–30 cm) (50,51). For medium- and high-energy photon emitters, a gaussian function in combination with decreasing exponential terms can be used to fit the measured CDR (50,51).…”
Section: Quantitative Spect Techniques For Nonuniform Dosimetrymentioning
confidence: 99%
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