Comparison between two iodine-125 brachytherapy implant techniques: pre-planning and intra-operative by various dosimetry quality indicators

Matzkin, Haim; Kaver, Issac; Bramante-Schreiber, Letizia; Agai, R.; Merimsky, Ofer; Inbar, Moshe

doi:10.1016/s0167-8140(03)00242-1

Cited by 38 publications

(23 citation statements)

References 20 publications

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“…A significant improvement of the V100 post and D90 post values by changing the implant technique was reported by Matzkin et al [14]. In their series, the preplan method was inferior to the results obtained by intraoperative planning: the D90 post increased from 53% to 113% and V100 post from 58% to 95%.…”

Section: Discussionmentioning

confidence: 72%

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Evaluation of Dose-Volume Histograms after Prostate Seed Implantation

et al. 2004

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Section: Discussionmentioning

confidence: 72%

“…A potential influence of the implantation technique as described by Matzkin et al [14] is difficult to assess in the results presented here. Only five patients were treated by intraoperative planning, and four of these belong to group 3.…”

Section: Discussionmentioning

confidence: 80%

Evaluation of Dose-Volume Histograms after Prostate Seed Implantation

et al. 2004

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“…35 Stock and Stone were the first to demonstrate that the D90 (the dose delivered to 90% of the prostate volume as outlined using postimplant CT images) was associated with better outcomes. 36 Matzkin et al 37 in Tel Aviv switched to this technique after treating 142 patients in the Seattle manner. They found that the subsequent 214 patients required less seeds, and had vastly improved dosimetric results with a mean D90 increase from an alarming 53% of the prescribed dose in the Seattle technique cohort to an acceptable 114%.…”

Section: 32mentioning

confidence: 99%

Permanent prostate brachytherapy: a century of technical evolution

Acher

Morris

Popert

et al. 2006

Prostate Cancer Prostatic Dis

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Purpose: To summarise the practical aspects of the development of techniques of interstitial permanent prostate brachytherapy (PPB) implantation. Prostate brachytherapy dates back to Pasteau's publication in 1913 describing the insertion of a radium capsule into the prostatic urethra to treat carcinoma of the prostate. Various implantation methods were employed but with unsatisfactory results until the development of the transrectal ultrasound in the 1980s. The subsequent two-stage Seattle technique allowed for a planned homogenous distribution of radioactive sources throughout the gland resulting in biochemical control comparable to surgical and external beam radiotherapy series. With the advent of advanced computer software and improved imaging, the technique has developed accordingly to a single stage procedure with ontable dosimetric assessment. The principles of targeting dose to the prostate while avoiding surrounding organs at risk remain as relevant today as nearly a century ago. There is an array of techniques to consider for the novice PPB provider. Whether the evolution of PPB techniques will translate into improved biochemical control is yet to be seen.

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“…23,24 Patients were scheduled to receive a target-matched peripheral dose of 145 Gy (preplan method) or 160 Gy (intraoperative method) according to the American Association of Physicists in Medicine Task Group 43 guidelines. 25 All underwent a computed tomography (CT)-based postimplant dosimetry evaluation at 1 month.…”

Section: Brachytherapymentioning

confidence: 99%

Sexual function after permanent 125I-brachytherapy for prostate cancer

et al. 2004

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We prospectively assessed patients' erectile function (EF) using the International Index of Erectile Function (IIEF) and a global assessment questionnaire (GAQ) following permanent 125 Ibrachytherapy for localized prostate cancer. Of 378 treated patients, 220 had a minimal 2-y follow-up and 131/220 were sexually active prior to brachytherapy, with an EF domain score of Z11 (study group). Patients were allowed sildenafil at any time of the study. The patients' mean EF score, without excluding patients who used sildenafil, dropped within 3 months after brachytherapy, recovered at the end of the first year and remained unchanged for at least up to 2 y after treatment regardless of the addition of neoadjuvant hormone therapy to 125 Ibrachytherapy. Analysis of the GAQ revealed that 80% of the patients were satisfied with their sexual function up to 3 y after treatment. Any detrimental effect of permanent brachytherapy with or without the addition of hormone therapy on EF is reversible, and recovery is expected at 1 y after treatment in most patients.

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Comparison between two iodine-125 brachytherapy implant techniques: pre-planning and intra-operative by various dosimetry quality indicators

Cited by 38 publications

References 20 publications

Evaluation of Dose-Volume Histograms after Prostate Seed Implantation

Evaluation of Dose-Volume Histograms after Prostate Seed Implantation

Permanent prostate brachytherapy: a century of technical evolution

Sexual function after permanent 125I-brachytherapy for prostate cancer

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