Comparison between optical coherence tomography and fundus fluorescein angiography for the detection of cystoid macular edema in patients with uveitis

Optical coherence tomography imaging in uveitis

“…This correlation showed significant difference depending on the OCT pattern and was strongly dependent on the presence of CME. A negative correlation between central foveal thickness and visual acuity has also been described in other studies [43,45,47,49]. Although DME was found to be associated with poor visual recovery after treatment [50], some studies point to a negative visual outcome in patients with uveitic CME [45,48,51,52].…”

“…Optical coherence tomography is suitable for detecting and monitoring uveitic macular edema [43,44]. It provides important information about the fluid distribution in eyes with macular edema and the morphology of the vitreoretinal interface.…”

Optical coherence tomography—a review of the principles and contemporary uses in retinal investigation

“…A recent study showed OCT to be highly sensitive (96%) and specific (100%) in the detection of oedema in patients with uveitis, more sensitive than both biomicroscopy alone and fluorescein angiography. 42 Z-plane imaging is also useful in describing the morphological appearance of diffuse diabetic macular oedema. A recent OCT study has shown Eye two patterns of diabetic macular oedema, that is, a domed appearance where the fluid everts the fovea and a diffuse appearance where the inner retinal contour is flat.…”

Macular auto-fluorescence is a follow-up parameter for cystoids macular edema

“…It is necessary to have a non-invasive, routine method to detect the response of the treatments. Fundus fluorescein angiography (FFA) and optical coherence tomography (OCT) have been accepted as the gold standards for the diagnosis of macular edema [1]. Leakage of the micro-vessels in the macular eye, as well as the morphology of macular edema can be visualized with FFA.…”

“…Macular thickening, the shape of the sub-retinal spaces and the presence of vitreal traction can be observed by OCT, providing precise evaluation of retinal pathology in CME. However, the information of intuitive structure and overall morphology of ME is less evident [1][2].…”