Comparison between choroidal thickness in patients with diabetic retinopathy and normal individuals using enhanced-depth imaging spectral-domain optical coherence tomography

Ghonemy, Khaled El; Rajab, Ghada Z; Ibrahim, Asmaa M; Gohar, Ibrahim M.I.

doi:10.4103/djo.djo_6_17

Cited by 3 publications

(3 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Its severity is closely related to elevated HbA1c level, duration of diabetes, comorbidities such as hyperlipidemia and hypertension, puberty, and pregnancy (21) . The choroidal and retinal vascular structures in diabetic patients have been reported to be affected even without developing retinopathy, based on the OCT studies in recent years (10,22) . The risk of retinopathy progression was noted to be significantly high in pregnant diabetic women (23) .…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…With the help of the enhanced deep imaging mode of the OCT, the choroid layer has been shown to be affected in diabetic patients (10,11,22,30,31) . It has been established that a decrease in the choroidal thickness in diabetic patients is associated with the worsening of retinopathy (22) . This could be attributed to the thinning of the choriocapillaris layer, causing hypoxia especially in the outer retinal folds, and increased vascular endothelial growth factor levels related to the hypoxia.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Evaluation of the relationship between HbA1c level and retina choroidal thickness in patients with gestational diabetes mellitus

Kahveci

Ekinci

2022

ABO

View full text Add to dashboard Cite

To investigate the effect of hemoglobin A1c level on central macular thickness and central, nasal, and temporal choroidal thickness in patients with gestational diabetes mellitus. Methods: This retrospective study included 41 patients who had been diagnosed with gestational diabetes mellitus and undergone a 75-g oral glucose tolerance test between 24 and 28 weeks of gestation. They were divided into two groups based on their hemoglobin A1c level (group 1: hemoglobin A1c <6.0% and group 2: hemoglobin A1c ≥6.0%). All patients underwent a complete ophthalmologic examination. The central macular thickness and central, nasal, and temporal choroidal thickness were measured using optical coherence tomography. Results: Of the 3,016 pregnant women screened, 7.5% (n=228) were diagnosed with gestational diabetes mellitus during the study period and 41 of these patients were included in the study. Group 1 comprised 48 eyes from 24 patients and Group 2 consisted of 34 eyes of 17 patients. The average body mass index values were 30.8 ± 3.3 and 35.1 ± 9.0, respectively (p=0.002). The insulin use rates were 29.2% and 76.5%, respectively (p=0.000). Mean central macular thickness values were 250.8 ± 14.3 µm and 260.9 ± 18.1 µm, respectively, and the difference was significant (p=0.008). Conclusions: Although the body mass index and central macular thickness values were significantly higher in Group 2, there was no difference in the central, nasal, and temporal choroidal thickness between the two groups.

show abstract

Section: Discussionmentioning

confidence: 99%