Comparison between Brain Tissue Gray and White Matters in Tension Including Necking Phenomenon

Abstract

Characterizing the differences between the mechanical properties of brain tissue gray and white matters is of importance in biomechanics of brain tissue and may find a variety of different applications in medicine. In this study, a comparison has been made between mechanical behavior of bovine brain tissue white and gray matters. Through a linear elastic theory and using Bridgman method, necking phenomenon is considered for brain tissue in tension test. Results show that gray and white matters have different mechanical properties and differences between true and nominal values (the effect of cross section changes of the samples during the test) are not negligible. Besides, it is shown that for certain strains, linear elastic theory is acceptable for brain tissue modeling. These results are in agreement with the literature.

Time-harmonic magnetic resonance elastography of the normal feline brain

“…Our data also showed that the difference between grey and white matter per feline subject was small but statistically significant, where white matter was stiffer than grey. Although some disagreement on the relative stiffness of white versus grey matter has appeared in the literature, our results are consistent with the conclusions reached in the majority of studies (Green et al (2008); Mehdizadeh et al (2008); Miller et al (2000); Miller and Chinzei (2002); Shuck and Advani (1972); Soza et al (2005)). Here, we did not observe the sizable differences between white and grey matter reported by Kruse et al but found much smaller differences similarly to Green et al …”

SiC for Brain–Machine Interface (BMI)

“…The third major issue that has received a lot of attention in recent years is the effect of micromotion. The CNS system is composed of very soft tissue (approximate Young's modulus between 3 and 20 kPa), and floats suspended in a thin layer of cerebral-spinal fluid [87,88]. The current hypothesis originates from the fact that many of the materials implanted, like Si and tungsten electrode wires (Young's modulus of 170 and 400 GPa, respectively), have a mechanical mismatch with the softer brain tissue leading to increased strain and stress forces acting on the neuronal tissue [83,88,89].…”

Mechanical Impedance of Cerebral Material

“…It is therefore essential to carry out measures to the Interior of this frequency band. Because of the impossibility of technical and legal studies of human in vivo, they have been supplanted by studies in vitro performed in low proportion on humans [2][3][4], and largely on animals like pigs [5][6][7][8] and monkey [9][10][11].…”