Comparison 0f effect of Antibiotics,Natural Honey and plant ExtractsonE.coliisolated from different clinical cases

Abstract

200 different clinical samples were collected from patients with Burns infections, wound infections, urinary Tract Infections & diarrhea for a period from March to August, 2017. Total of 403 bacterial isolates were identified, the gram negative bacteria E.coli represented329 (48.9%). The percentages of E.coliisolatesare different depending on isolation sources, urinary Tract Infections have the highest rate of isolation (72.2%). Bacterial sensitivity against10different antibiotics were tested, all isolates showed full resistance againstPenicillins & Cephalosporins while they have high sensitivity for Nitrofurantion. The other antibiotics have different effects depending on the isolation sources. Natural Honey has high antibacterial activity for E.coliwithout any influence withisolation sources with MIC,15%. Antibacterial activity ofthe EthanolicExtracts (95%) for four plants: Allium sativum,Paganum harmala,Nigella sativum & Myrtus communs. All of this have high inhibitory effect onE.coliisolates without any influence of the isolation sources, but Allium sativum extract has the highest effect with inhibition zone diameters (20.1-32.0) mm.

Investigation of some Bacterial Species Contaminated with some Foods in Baghdad Regions

“…shows the resistance of Proteus hauseri to the Amoxillin and Methicillin, and their sensitivity to other antibiotics, the largest inhibition diameter of 30 mm at a 30 mg/ml using the Chloramphenicol. [19] They explained that the cause of resistance to beta-lactam antibiotics is due to the ability of intestinal bacteria to produce beta-lactamase enzymes that break the betalactam ring involved in the formation of the nucleus of these antibiotics, which leads to the emergence of sensitivity to nitrofurantoin. The indiscriminate use of antibiotics can be responsible for the pattern of multiple resistance of the organism.…”