Comparision of efficacy of local administration of contractubex & corticosteroids for hypertrophic scar in maxillofacial region

Abstract

Hypertrophic scarring following surgical procedures & trauma are a great concern for patients and a challenging problem for clinicians. The therapeutic management of hypertrophic scars is a problem that has not yet been satisfactorily solved. Contractubex® ointment and intra lesional injection of corticosteroids have been used effectively for treatment and prevention of hypertrophic scars. However very few data is available to determine the efficacy of Contractubex® ointment and intra lesional injection of corticosteroids for the treatment of hypertrophic scar. Two study groups were made with 10 patients in each group. Patients in Group 1 treated with Contractubex® and patients in Group 2 treated with intra lesional corticosteroid (Triamcinolone acetonide). Scar was analyzed with Vancouver Scar Scale (VSS) at 2 weeks, 6 weeks and 12 weeks. The collected data was statistically analyzed. We found that the difference between before and after treatment scores for each of the groups was statistically significant (p < 0.05). The mean of the before and after treatment difference for the Group 1 (Contractubex® ) was 4.7 while that of group 2 (Corticosteroids) was 2.8. This demonstrated a significant superiority of the Contractubex® treatment compared to corticosteroid treatment. The difference between treatment responses for both the groups was statistically significant (p < 0.05). Excellent to good responses were reported in 90% of the Group 1 (Contractubex®) patients and 30% of Group 2 (Corticosteroids).

Scar prevention by low level laser therapy on surgical wound post hand flexor tendon repair

“…Minimal response was given for an improvement of between one and three points. No response was assigned to those patients who had no change in the Vancouver scar scale [9].…”