Study design: Retrospective cohort studyObjective: To investigate the potential of technetium-99m-mercaptoacetyltriglycine (99mTc-MAG-3) renal scintigraphy in predicting maximal detrusor pressure in the early stages of spinal cord injury (SCI).Setting: Tertiary rehabilitation facility Methods: Medical records of individuals with SCI admitted between January 202 and April 2023 who underwent both 99mTc-MAG-3 renal scintigraphy and urodynamic study within 90 days of SCI onset were retrospectively reviewed. Pearson's coe cient analysis was performed to determine the relationship between 99mTc-MAG-3 renal scintigraphy ndings and urodynamic study ndings. Multivariate linear regression analysis was performed to determine the best predictors of maximal detrusor pressure.Multivariate logistic regression analysis was performed to determine risk factors for high detrusor pressure.Results: Ninety-four participants were enrolled in this study. The Pearson's correlation analysis showed that ERPF and ERPF (% predicted) were signi cantly correlated with maximal detrusor pressure. The multivariate linear regression analysis demonstrated that ERPF (% predicted) was a signi cant predictor of maximal detrusor pressure. The multivariate logistic regression analysis showed that ERPF (% predicted) was signi cantly associated with high detrusor pressure. Receiver operating characteristic curves demonstrated that the predictive model had an area under the curve of 0.725, and the cut-off value for ERPF (% predicted) was 64.05%, with a sensitivity of 1.000 and speci city of 0.429.
Conclusion:These results suggest that 99mTc-MAG-3 renal scintigraphy may be useful for predicting high detrusor pressure in early SCI, and may guide the timing of urodynamic studies in individuals with early SCI for appropriate management of neurogenic bladder.