Comparing the effects of manual acupuncture, electroacupuncture, and transcutaneous electrical nerve stimulation on chronic tinnitus: a randomized controlled trial

Kim, Bong Hyun; Moon, Young Kyun; Kim, Min Hee; Nam, Hae Jeong

doi:10.1016/j.imr.2020.100409

Cited by 13 publications

(43 citation statements)

References 21 publications

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“…Transcutaneous electrical acupoint stimulation (TEAS) is a non-invasive acupuncture-like technique, which is easy to apply in young children. The physiological effects of TEAS are similar to that of EA on analgesia [ 39 ] and other diseases [ 40 ]. Acupuncture intervention at an early age or during developmental critical periods may be beneficial to the facilitation of AIDRR (Activate, Integrate, Discriminate, Respond, Reward) neural loop [ 41 ].…”

Section: Acupuncture Can Cause Prosocial Effects Of Oxytocinmentioning

confidence: 99%

Acupuncture and oxytocinergic system: The promising treatment for autism

Pei

2021

Translational Neuroscience

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Autism spectrum disorder (ASD) is a group of heterogeneous neurodevelopmental disorders characterized by impairments activities without efficient pharmacological therapies in social interaction, speech and stereotypic patterns. Clinical studies have shown the efficacy of acupuncture as an alternative therapy for autism. The effectiveness of acupuncture as an alternative treatment for autism has been demonstrated through clinical trials. However, the molecular mechanisms that underlie these effects remain unclear. Due to its profound pro-social, anxiolytic, stress management effects, and its potential use for the treatment of psychiatric disorders associated with altered socioemotional competence, oxytocin (OT) released from the hypothalamus has attracted considerable interest. In the past decade, a number of clinical and animal studies have shown that OT administration effectively reduces core symptoms of ASD, especially social behavior deficits. Recently, the endocannabinoid system has emerged as a promising target for the treatment of autism. OT was found to facilitate the endocannabinoid-mediated social reward processes in the nucleus accumbens of the mouse brain. Furthermore, serotonin and dopamine are involved in the reward response mediated by OT. In view of these findings, we conclude that acupuncture may produce therapeutic effects on autism by triggering the hypothalamic oxytocin system, which in turn activates the release of neurotransmitters such as endocannabinoids, dopamine and serotonin. This would be a valuable guide for further research on the mechanism of treatment of autism with acupuncture.

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Section: Acupuncture Can Cause Prosocial Effects Of Oxytocinmentioning

confidence: 99%

Acupuncture and oxytocinergic system: The promising treatment for autism

Pei

2021

Translational Neuroscience

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“…9 Han concluded that acupuncture or electrical stimulation in specific frequencies applied to certain body sites can facilitate the release of specific neuropeptides in the central nervous system (CNS), which subsequently elicit physiologic effects and activate selfhealing mechanisms. 10-14 Kim et al 15 in a recent trial study showed that electroacupuncture is more effective than manual acupuncture and TENS (transcutaneous electrical nerve stimulation) for people with chronic tinnitus.…”

Section: Introductionmentioning

confidence: 99%

Neuropuncture, an Effective Treatment Method for Patients with Subjective Tinnitus Accompanied with Hearing Loss: Case Reports

Law¹,

Corradino²

2021

Medical Acupuncture

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Background: Tinnitus is a serious health condition. It can be debilitating and as such negatively affects a patient's quality of life. People with tinnitus often experience distress, depression, anxiety, frequent mood swings, sleep disturbances, irritability, frustration, poor concentration, and possible suicidal thoughts or actions. Objective: The goal of this article is to introduce an acupuncture system, based on neurophysiology and termed Neuropuncture, as a possible effective treatment method for tinnitus accompanied with and/or secondary to hearing loss. The treatment protocol works by targeting the greater auricular nerve, trigeminal nerve, cervical plexus, and auditory cortex to neuromodulate, neurorehabilitate, and neuroregulate the nervous system and repair the nerve damage. Design: Three case studies are presented herein as examples. They are based on neurophysiologic mechanism of tinnitus and hearing loss, treatment principle, treatment methods, and subjective and clinically objective tests. Electroacupuncture protocols used various frequencies with microcurrent and millicurrent stimulation. Conclusions: Neuropuncture system is an effective treatment for patients with acute and chronic subjective tinnitus and hearing loss. Results showed reduction of tinnitus and partial restoration of hearing loss. Further research and possible large-scale trial studies are suggested.

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“…Electroacupuncture reduced the tinnitus handicap inventory (THI) score significantly, in more than ten points. 8 Low-frequency repetitive transcranial magnetic stimulation (TMS) of the auditory cortex has been proposed as a novel therapeutic tool for tinnitus. 9 The TMS technique is noninvasive, and applies the principles of electromagnetism to carry an electrical current into the brain.…”

Section: Introductionmentioning

confidence: 99%

“…Several therapeutic approaches have been attempted to alleviate tinnitus, but the effectiveness of these treatments is inconsistent. Kim et al 8 examined the efficacy of manual acupuncture, electroacupuncture and transcutaneous electrical nerve stimulation in the treatment of chronic tinnitus, and they found no improvement in the loudness and annoyance of tinnitus. Electroacupuncture reduced the tinnitus handicap inventory (THI) score significantly, in more than ten points.…”

Section: Introductionmentioning

confidence: 99%

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Assessment of the Effectiveness of Transcranial Magnetic Stimulation in Subjective Tinnitus

Aydın

Erkan

Gündoğdu³

et al. 2020

Int Arch Otorhinolaryngol

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Introduction Increases in spontaneous activity in the neurons of the auditory cortex are presumed as the pathophysiology of tinnitus. Objective To investigate the effectiveness of transcranial magnetic stimulation (TMS) in the treatment of tinnitus. Methods A total of 62 patients between the ages of 22 and 74 with chronic subjective tinnitus were enrolled in the study. The inclusion criteria were normal findings on an otolaryngologic examination and normal ranges of complete blood count, routine biochemical parameter levels, thyroid function, air-bone gap on pure-tone audiometry, and middle-ear pressure and stapedial reflex on tympanometry. The patients were randomized into 2 groups: 40 patients were placed in the treatment for TMS (tTMS) group, and the rest (22 patients) were placed in the sham TMS group. The frequency and severity of the tinnitus, as well as the tinnitus handicap inventory (THI) score of each patient were measured before and one month after the treatment, and the values were statistically evaluated. Results We observed a statistically significant improvement in the tTMS group (p < 0.05 and p < 0.05 respectively) regarding the THI and tinnitus severity scores. The sham TMS group showed no significant improvement in terms of the THI (p > 0.05). However, the tinnitus severity showed a significant increase in this group (p < 0.05). The comparison of differences in the changes in the THI and the tinnitus severity scores showed a significant statistical improvement in the tTMS group compared with the sham TMS group (p < 0.05 and p < 0.05 respectively). Conclusion Transcranial magnetic stimulation was found to be effective in the treatment of tinnitus, and may be adopted as a treatment for tinnitus after further comprehensive studies.

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Comparing the effects of manual acupuncture, electroacupuncture, and transcutaneous electrical nerve stimulation on chronic tinnitus: a randomized controlled trial

Cited by 13 publications

References 21 publications

Acupuncture and oxytocinergic system: The promising treatment for autism

Acupuncture and oxytocinergic system: The promising treatment for autism

Neuropuncture, an Effective Treatment Method for Patients with Subjective Tinnitus Accompanied with Hearing Loss: Case Reports

Assessment of the Effectiveness of Transcranial Magnetic Stimulation in Subjective Tinnitus

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