Comparing the Effects of Distilled Rehmannia glutinosa, Wild Ginseng and Astragali Radix Pharmacopuncture With Heart Rate Variability (HRV): A Randomized, Sham-controlled and Double-blind Clinical Trial

Yook, Tae-Han; Jungsuk, Yu; Lee, Hwi-Yong; Song, Beomyong; Kim, Lakhyung; Jungdu, Roh; Jinchul, Shin; Lim, Sabina

doi:10.1016/s2005-2901(09)60061-3

Cited by 15 publications

(10 citation statements)

References 3 publications

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“…Another study suggested that P. ginseng suppresses apoptosis by regulation of Bcl-2 and caspase-3 during hypoxia/reoxygenation in neonatal rat cardiomyocytes [43]. The effects of wild ginseng and astragali radix pharmacopuncture have been compared on the autonomic nervous system and heart rate variability [44]. In addition, ginsenoside Rg 1 protects rat cardiomyocyte from hypoxia/reoxygenation oxidative injury via antioxidant and intracellular calcium homeostasis [45].…”

Section: Efficacy Of Improving Myocardial Protectionmentioning

confidence: 99%

Cardiovascular Diseases and Panax ginseng: A Review on Molecular Mechanisms and Medical Applications

Kim

2012

Journal of Ginseng Research

209

142

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Section: Efficacy Of Improving Myocardial Protectionmentioning

confidence: 99%

Cardiovascular Diseases and Panax ginseng: A Review on Molecular Mechanisms and Medical Applications

Kim

2012

Journal of Ginseng Research

209

142

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“…Wild ginseng pharmacopuncture in healthy adults tended to activate the autonomic nervous system, particularly the sympathetic nervous system [44]. Another clinical trial showed higher parasympathetic and lower sympathetic activity modulation after the administration of Kampo including ginseng [45].…”

Section: Discussionmentioning

confidence: 99%

Effect of Korean red ginseng on cold hypersensitivity in the hands and feet: study protocol for a randomized controlled trial

Park

Kim

et al. 2013

Trials

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BackgroundCold hypersensitivity in the hands and feet (CHHF) is one of the most common complaints among Asians, especially in women. Korean red ginseng (KRG), which is a steamed form of Panax ginseng, has vasodilating action in the peripheral vessels and increases blood flow under cold stress. However, few studies have evaluated the effect of KRG on cold hypersensitivity.Methods/DesignThis trial is a randomized, double-blind, placebo-controlled trial in 80 CHHF patients. The trial will be implemented at Kyung Hee University Hospital at Gangdong in Seoul, Korea. The participants will take KRG or a placebo for eight weeks, after which they will be followed-up for four weeks. During the administration period, six capsules of 500 mg KRG or placebo will be provided twice a day. The primary outcome is change of skin temperature in the hands between baseline and after treatment. The secondary outcomes include the visual analogue scale scores of cold hypersensitivity in the hands, change of skin temperature and the VAS scores of cold hypersensitivity in the feet, the recovery rate of the skin temperature by the cold stress test of the hands, the distal-dorsal difference of the hands, power variables of heart rate variability, and the 36-item short form health survey.DiscussionThis study is the first trial to evaluate the efficacy of KRG on CHHF by using infrared thermography. Our study will provide basic evidence regarding CHHF.Trial registrationCliniacalTrials.gov NCT01664156

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“…In addition, some of the meridian points have opposite effects, which are contrary to other points. LI11 [14] and GB21 [19] increase sympathetic nerve activity, while BL13 decreases it [20]. Since the point combinations in the holistic therapies include meridian points with bi-directional regulation of the autonomic balance, they can be applied to various pathological conditions in a balanced manner.…”

Section: Acupuncture and Moxibustion For Systemic Regulation Of The Amentioning

confidence: 99%

Acupuncture and moxibustion for stress-related disorders

Kondo

Kawamoto

2014

BioPsychoSocial Med

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Acupuncture and moxibustion, which medical doctors are licensed by the government of Japan to perform, can improve the psychological relationship between doctors and patients, especially when it is disturbed by a “game”, a dysfunctional interpersonal interaction that is repeated unintentionally. This advantage is due to the essential properties of acupuncture and moxibustion. Acupuncture and moxibustion are helpful in treating somatoform disorders, especially musculoskeletal symptoms. In Japan, a holistic acupuncture and moxibustion therapy called Sawada-style has been developed. This is based on fundamental meridian points that are considered to have effects on central, autonomic nervous, immune, metabolic, and endocrine systems to regulate the whole body balance. In addition, some of the fundamental points have effects on Qi, blood, and water patterns associated with major depression, generalized anxiety disorder, eating disorders, and somatoform disorders. The fixed protocol of Sawada-style would be suitable for large-scale, randomized, controlled studies in the future. Recent systematic reviews indicate that electroacupuncture would be a useful addition to antidepressant therapy for some symptoms accompanying fibromyalgia. Acupuncture and moxibustion are also recommended for irritable bowel syndrome, instead of Western drug therapy. Surprisingly, the dorsal prefrontal cerebral cortex, which is associated with a method of scalp acupuncture applied for gastrointestinal disorders, has been found to be activated in patients with irritable bowel syndrome. It is quite possible that regulation of this cortical area is related to the effect of scalp acupuncture. This acupuncture method can be effective not only for irritable bowel syndrome but also for other stress-related gastrointestinal disorders.

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Comparing the Effects of Distilled Rehmannia glutinosa, Wild Ginseng and Astragali Radix Pharmacopuncture With Heart Rate Variability (HRV): A Randomized, Sham-controlled and Double-blind Clinical Trial

Cited by 15 publications

References 3 publications

Cardiovascular Diseases and Panax ginseng: A Review on Molecular Mechanisms and Medical Applications

Cardiovascular Diseases and Panax ginseng: A Review on Molecular Mechanisms and Medical Applications

Effect of Korean red ginseng on cold hypersensitivity in the hands and feet: study protocol for a randomized controlled trial

Acupuncture and moxibustion for stress-related disorders

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