Comparative Study on the Synergistic Action of Garlic Synthesized and Citrate Capped Silver Nanoparticles with β-Penem Antibiotics

Abstract

Resistance to antimicrobial agents by pathogenic bacteria has emerged in recent years and is a major challenge for the health care industry. For developing a cheap broad-active agent that can be applicable against different pathogens, it is necessary to develop an alternative source for normal antibacterial agents. This paper mainly focuses on the combined action of green as well as citrate synthesized silver nanoparticles and β-penem antibiotics, which are β-lactam antibiotics with penem rings. These silver nanoparticles synergistic potential helps in the enhancement of antibacterial activity of broad spectrum antibiotics. The synergistic actions of citrate capped silver nanoparticles (Ag-NPs) were compared with that of garlic (Allium sativum) synthesized silver nanoparticles together with action of antibiotics, ampicillin and amoxyclav, and some of the pathogenic organisms showed an increase in the action of antibiotics.

Biophysical and Characterizations of Silver Nanoparticles used as Salmonella typhi Detector

“…When the reducing agents were mixed with aqueous solution of the silver nitrate, they started to convert the color from colorless to yellowish brown due to reduction of silver ion, which indicated the formation of silver nanoparticles (Mukunthan et al, 2011;Hari et al, 2013). The reduction of silver ionwas mainly due to the presence of photo chemicals such as flavonoids, phenols, and ascorbic acid, present in Choreospondias axillaris extract.…”

Nanomaterials in the Management of Gram-Negative Bacterial Infections

“…Recently, numerous NPs, such as silver NPs, zinc oxide NPs, and cationic surfactant NPs, have been used for bacterial infection treatment [30][31][32]. The antibacterial potential of silver NPs generally depends on the particle size, shape and surface modification [33][34][35][36]. The loading of antibacterial moiety into the silver NPs also enhances its antimicrobial activity [37,38].…”