2007
DOI: 10.1016/j.toxicon.2007.06.002
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Comparative study on extracts from the tissue covering the stingers of freshwater (Potamotrygon falkneri) and marine (Dasyatis guttata) stingrays

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Cited by 60 publications
(72 citation statements)
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“…A study of tissue extracts from the stingers of freshwater and marine stingrays showed that both tissue extracts had gelatinolytic, caseinolytic, and fibrinogenolytic activity but hyaluronidase activity was detected only in the extracts from freshwater stingrays. 22 In our case series, no patient injured by a freshwater stingray developed skin necrosis. The risk of developing skin necrosis is likely related to the venom load.…”
Section: Discussionmentioning
confidence: 58%
“…A study of tissue extracts from the stingers of freshwater and marine stingrays showed that both tissue extracts had gelatinolytic, caseinolytic, and fibrinogenolytic activity but hyaluronidase activity was detected only in the extracts from freshwater stingrays. 22 In our case series, no patient injured by a freshwater stingray developed skin necrosis. The risk of developing skin necrosis is likely related to the venom load.…”
Section: Discussionmentioning
confidence: 58%
“…The anticoagulant activity might be due to the presence of fibrin (ogen) olytic enzyme [23] . The studies on extracts of tissue covering stingers of marine and freshwater stingrays (Dasyatis gutata and Potamotrygon falkneri) showed anticoagulant activities, edematogenic, gelatinolytic, caseinolytic and fibrinogenolytic activities reported that anticoagulant activity of crude sample from molluscan species ranged from 70 to 120 USP units/mg whereas the activity ranged from 130 to 150 USP units/mg after purification [24][25][26] .…”
Section: Discussionmentioning
confidence: 99%
“…Geralmente estas funções são resultantes da lise celular enzimática oriunda das fosfolipases A 2 e C, enzimas comuns presentes em diversos organismos como répteis, anfíbios e cnidários (GOMES et al, 2013). Componentes com atividades citolíticas como a atividade de fosfolipase foram relatadas em arraias de ambos os habitats tanto dulcícola como marinhas (BARBARO et al, 2007). No presente trabalho, foi observada tal atividade na peçonha bruta, corroborando com BARBARO et al (2007).…”
Section: Discussionunclassified
“…Componentes com atividades citolíticas como a atividade de fosfolipase foram relatadas em arraias de ambos os habitats tanto dulcícola como marinhas (BARBARO et al, 2007). No presente trabalho, foi observada tal atividade na peçonha bruta, corroborando com BARBARO et al (2007). O extrato de P. falkneri apresentou maior atividade na ausência de cálcio, entretanto a maior parte dos grupos de fosfolipases são Ca + dependentes (STÁBELI et al, 2012 (GWEE et al, 1994;GARNIER et al, 1995;GOMES et al, 2013 horas após a incubação com a peçonha (SIVAN et al, 2007).…”
Section: Discussionunclassified
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