Comparative study of temporary effect on the water content at different depths of the skin by hot and cold moisturizing formulations

Cortázar, Tania M.; Guzmán-Alonso, M.; Nóvoa, Helton José Dias de; Riaño, Michael Fernando Medina

doi:10.1111/srt.12185

Cited by 7 publications

(8 citation statements)

References 20 publications

(24 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The curve-fitted weight-loss was obtained using Levenberg–Marquardt algorithm that determined the three parameters values of the system ( k 1 , k 2 and k 3 ) that minimised the difference between the predicted and the experimentally observed total mass M ( t ) over time (Table 2 ). The initial proportions for bound and free water were considered based on that only 0.3 of the 98% of water in BC corresponds to free water and the remaining 97.7% is bound water [ 16 ]. Thus, at t = 0, B (0) = 0.977 and F (0) = 0.003.…”

Section: Resultsmentioning

confidence: 99%

Dehydration of bacterial cellulose and the water content effects on its viscoelastic and electrochemical properties

Rebelo

Archer

Chen

et al. 2018

Science and Technology of Advanced Materials

View full text Add to dashboard Cite

Bacterial cellulose (BC) has interesting properties including high crystallinity, tensile strength, degree of polymerisation, water holding capacity (98%) and an overall attractive 3D nanofibrillar structure. The mechanical and electrochemical properties can be tailored upon incomplete BC dehydration. Under different water contents (100, 80 and 50%), the rheology and electrochemistry of BC were evaluated, showing a progressive stiffening and increasing resistance with lower capacitance after partial dehydration. BC water loss was mathematically modelled for predicting its water content and for understanding the structural changes of post-dried BC. The dehydration of the samples was determined via water evaporation at 37 °C for different diameters and thicknesses. The gradual water evaporation observed was well-described by the model proposed (R 2 up to 0.99). The mathematical model for BC water loss may allow the optimisation of these properties for an intended application and may be extendable for other conditions and purposes.

show abstract

Section: Resultsmentioning

confidence: 99%

Dehydration of bacterial cellulose and the water content effects on its viscoelastic and electrochemical properties

Rebelo

Archer

Chen

et al. 2018

Science and Technology of Advanced Materials

View full text Add to dashboard Cite

show abstract

“…By offering a multiple frequency approach, it is possible to obtain different depth measurements, useful to differentiate water in the outer layers of the skin (stratum corneum, epidermis) from water in the underlying tissues. Edema in different skin layers, lymphedema, and related conditions can be assessed by measuring the tissue dielectric constant (TDC) . TDC values reflect body composition.…”

Section: Epidermal Hydration Measurement By Electrical Methodsmentioning

confidence: 99%

“…Edema in different skin layers, lymphedema, and related conditions can be assessed by measuring the tissue dielectric constant (TDC). [11][12][13][14] TDC values reflect body composition.…”

Section: Measurement Of Dielectric Constants and Hydration Depth Prmentioning

confidence: 99%

The revised EEMCO guidance for the in vivo measurement of water in the skin

Berardesca

Lodén²,

Serup

et al. 2018

Skin Research and Technology

120

130

View full text Add to dashboard Cite

The established methods for measurement of epidermal water content and TEWL have been supplemented with important new technologies including methods that allow imaging of epidermal water distribution and water depth profiles. A much more complete and sophisticated characterization of the various aspects of the dermal water barrier has been accomplished by means of today's noninvasive techniques; however, instrument standardization and validation remain a challenge.

show abstract

“…The ablation wavelength of 532 nm may have the additional advantage over other reported nail poration systems of not being tuned to the strong OH absorption peak (primarily from water). The water content of the nail plate (7-25%) is low compared to that of the nail bed (which is the same as that of the viable epidermis (70%)) [26,27]. Using lasers for nail poration based on the strong water absorption band around 3 µm is therefore likely to cause significant damage to the nail bed once the pore has been drilled through the nail.…”

Section: Fig 6 the Data Inmentioning

confidence: 99%

Precise laser poration to control drug delivery into and through human nail

Vanstone

Cordery

Stone

et al. 2017

Journal of Controlled Release

View full text Add to dashboard Cite

Drug treatment of diseases of the human nail remains a difficult challenge; topical therapy, in particular, is limited by very poor transport of active agents across the nail itself. The objective of this research was to examine the potential of controlled, and fibre-optic delivered, femtosecond laser light pulses to provide new pathways and opportunities for drug access to targets within and beneath the nail plate. Optical, confocal fluorescence and scanning electron microscopies demonstrated partial and complete laser poration of human nail samples, with the energy per pore and the exposure duration being the key modulating parameters that determined the extent of ablation achieved. Parallel measurements of the penetration of a model drug across laser-treated nails showed that complete poration resulted in essentially complete circumvention of the diffusion barrier, an array of 100 pores in 0.2cm area of nail permitting a 10-fold increase in initial drug uptake. Partial ablation of the nail created pores that extended to a range of depths; the nail material adjacent to the ablated area was rendered porous in appearance presumably due to local thermal perturbation of the nail structure. These openings offer, as a result, potential sites in which topical drug formulations might be sequestered post-poration and from which slow, sustained delivery of the active agent into and through the nail may be envisaged.

show abstract

Comparative study of temporary effect on the water content at different depths of the skin by hot and cold moisturizing formulations

Cited by 7 publications

References 20 publications

Dehydration of bacterial cellulose and the water content effects on its viscoelastic and electrochemical properties

Dehydration of bacterial cellulose and the water content effects on its viscoelastic and electrochemical properties

The revised EEMCO guidance for the in vivo measurement of water in the skin

Precise laser poration to control drug delivery into and through human nail

Contact Info

Product

Resources

About