Comparative Study of Tanacetum Species Growing in Bulgaria

Abstract

Chemical investigation of the Bulgarian species Tanacetum, parthenium, T. millefolium, T. achilleifolium, T.corymbosum and T. macrophyllum afforded in addition to 24 known sesquiterpene lactones a new 12, 8-eudesmanolide 22. Besides, four known highly oxigenated terpenoids and a new keto-diol 30 of the rare iphionane skeleton were also isolated. The structures were elucidated on the basis of their spectral properties. The accumulation of the different sesquiterpene lactones in the studied species and there classification is discussed

An Integrative Approach to Selected Species of Tanacetum L. (Asteraceae): Insights into Morphology and Phytochemistry

“…Whereas several studies on the chemosystematics of the Asteraceae in general were undertaken by some researchers ([ 4 , 5 , 6 , 7 ] and literature therein), literature shows few attempts to detail the chemical classification of the genus Tanacetum [ 8 , 9 , 10 , 11 ]. The occurrence of EOs, bitter substances, sesquiterpene lactones, flavonoids, and other constituents [ 9 , 12 , 13 , 14 , 15 , 16 , 17 , 18 ], along with the wide range of the related biological activities, were the subject of previous papers and reviews on Tanacetum . Antioxidant [ 19 , 20 , 21 ], immunomodulatory [ 22 ], cytotoxic [ 20 , 21 ], anti-inflammatory, and growth-regulating properties [ 20 , 23 ] were documented, in addition to antifeedant, insecticide, and antimicrobial activities [ 21 , 24 , 25 , 26 ].…”

Metabolites from the Aerial Parts of the Sicilian Population of Artemisia alba

“…Hydroxydavanone (3) has been previously isolated from the aerial parts of Tanacetum vulgare [19], T. millefolium and T. achilleifolium [20], from the roots of Pyrethrum santolinoides [21] and from the aerial parts of several species of Artemisia: A. maritima L. [22], A. inculta [23], A. pallens [24,25], A. laciniata [26], A. herba-alba, A. reptans [27], A. lobelii. ssp.…”

Feverfew (Tanacetum partheniumSchultz Bip.)

“…13,14 The highest concentrations of parthenolide occur in the fl owering tops and leaves, whereas the stalks and roots contain very small amounts of parthenolide. 16 Lipophilic fl avonols in the leaves and fl owers of feverfew include tanetin (6 -hydroxykaempferol 3,7,4 ′ -trimethyl ether), 6 -hydroxykaempferol 3,7 -dimethyl ether, quercetagetin 3,7 -dimethyl ether and quercetagetin 3,7,3 ′ -trimethyl ether. 2 Feverfew varieties with a light green -yellow colored variety have signifi cantly higher mean parthenolide concentrations (1.61% ± 0.61%, dry weight) than darker -leafed varieties ( < 0.5%).…”