Comparative study of serum lipid profile between prehypertensive and normotensive

Abstract

Background: Prehypertensive subjects have greater risk of developing hypertension than the normotensive subjects. Studies have shown that lipid profile is altered in hypertensive patients as compare to normotensive subjects. But not much is documented about lipid profile in prehypertensives. So the present study is done to compare the serum lipid profile among prehypertensive and normotensives and to correlate the blood pressure and lipid profile in prehypertensives. Methods: 50 prehypertensive and 50 normotensive subjects were recruited from the general population. Blood pressures were recorded and serum lipid profiles were measured and compare using student t test. Correlation of serum lipid profile and blood pressure was done using person correlation. Results: The study results showed significant increased in total cholesterol, LDL, VLDL and serum triglyceride level in prehypertensives compare to normotensives. While there is no significant change in HDL level in prehypertensive compare to normotensive. And there is also a significant correlation between blood pressure and lipid profile in prehypertensive subjects. Conclusion: Lipid profile is altered in prehypertensives compare to normotensives. That's why timely diagnoses and life style modification is required in prehypertensives.

Evaluation of Lipid Profile Among Prehypertensive and Normotensive Patients: A Teaching Hospital based Study

“…While the maximum number of prehypertensive in a study conducted by Hitesh A. Jani et al was found to be 2nd to 3rd decade. [16] This present study shows the mean SBP and DBP of prehypertensives group were higher than those of normotensives group, which is much similar to that reported by Hitesh A Jani et al who observed that SBP & DBP in hypertensives. [16] …”

“…[ [16,17] From the present study we have found an association of dyslipidemia with prehypertension. A population study in china in 1154 subjects found that total cholesterol, LDL, VLDL, Triglyceride were significantly increased & HDL were significantly decreased in prehypertensives.…”

“…[17] The study conducted by Ravi Venkatachalam et al Hitesh A Jani too reported similar relation to lipid profile. [16,17] Choi K M et al did a study which aimed to determine the prevalence of prehypertension and hypertension and their association with risk factors. [18] They conducted their survey in 2001 over a population of 6074 in Korea they concluded that hypertension and prehypertension were common in Korea and about one-half of the hypertensive's have not be diagnosed.…”