Rapid eye movements (REMs) are a peculiar and intriguing aspect of REM sleep, even if their physiological function still remains unclear. During this work, a new automatic tool was developed, aimed at a complete description of REMs activity during the night, both in terms of their timing of occurrence that in term of their directional properties. A classification stage of each singular movement detected during the night according to its main direction, was in fact added to our procedure of REMs detection and ocular artifact removal. A supervised classifier was constructed, using as training and validation set EOG data recorded during voluntary saccades of five healthy volunteers. Different classification methods were tested and compared. The further information about REMs directional characteristic provided by the procedure would represent a valuable tool for a deeper investigation into REMs physiological origin and functional meaning.
I IntroductionRapid eye movements (REMs) represent a peculiar feature of REM sleep. They episodically occur mostly grouped in bursts and correspond to rapid saccades, similar to those occurring in the awake state when visual inputs are absent but imagined [1].In normal subjects, REMs timing seems to be governed by a nonlinear deterministic process [2]; moreover, their time density increases from early to late REM sleep episodes and it shows a cyclical pattern within each REM episode with periodical peaks, the first one occurring 5-10 minutes after REM sleep onset. Since the discovery of REM sleep, REMs have been associated to the scanning of dream scene. From then on, many authors have highlighted several issues concerning this hypothesis, and many conjectures on their functional meaning have been proposed. However, REMs physiological function remains controversial and poorly understood and this makes these ocular movements and their particular organization during the night an intriguing sleep aspect to be analyzed. Several In order to complete the REM analysis we present a classification stage aimed at discriminating the main spatial direction of each REM. To achieve this purpose, an ad hoc dataset has been populated using data obtained from electrooculographic (EOG) recordings. A list of possible classification features has been drawn up. Different classification methods have been then applied and for each one the optimal subset of features has been extracted using the Pudil's sequential forward floating selection method (PSFFS) [5]. The dataset and the supervised classifiers is described in section II. The performance of the classifiers obtained during a cross-validation stage will be illustrated and compared in section III.
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II Methods
A Experimental SettingsThe dataset for training and validation of the supervised classifiers has been experimentally obtained by using EOG recordings from five healthy volunteers (24-35 years old), instructed to perform eye movements in response to a trigger sound. In order to make the kinematics parameters as muc...