Comparative study of early-onset with late-onset primary Sjogren’s Syndrome

Abstract

BACKGROUNDThe onset of primary Sjögren's syndrome (pSS) is usually between 50 and 60 years of age, but it can also occurs in younger patients, in whom there is a higher prevalence of the important prognostic indicators: salivary gland enlargement, adenopathy, purpura and renal involvement, extraglandular involvement, vasculitis, hypocomplementemia, hypergammaglobulinemia, antinuclear antibody (ANA) and anti-Ro antibody. The objective of this study was to compare clinical and laboratory characteristics of early with late onset pSS. METHODS