“…Importantly, the improvement of SPR sensors has progressed with several aims: (1) enhancing the sensitivity; (2) securing selectivity to specific targets; and (3) increasing biocompatible stability. Furthermore, additional advancements in SPR sensors to secure an efficient performance should continue and several research groups proposed SPR sensors with highly improved performances using advanced fabrication and converged techniques, for instance, symmetric insulator-metal-insulator substrate based LRSPR [ 124 ], sensing performance improvement using a top dielectric nanoscale layer [ 124 , 125 ], a spectropolarimetric SPR sensor [ 126 , 127 ], and combined exciting localized and extended surface plasmon sensors with ultrahigh sensitivity [ 128 , 129 ]. On the other direction, the miniaturization of SPR sensors is also needed to increase utilization, and research groups have reported several prototypes of miniaturized SPR sensors [ 130 , 131 , 132 , 133 , 134 , 135 , 136 ].…”