Comparative study between: Carboxytherapy, platelet‐rich plasma, and tripolar radiofrequency, their efficacy and tolerability in striae distensae

Abstract

The three modalities of treatments proved to be effective clinically and histopathologically in treating both types of striae, which were well tolerated by the patients with minimal, transient side effects and our study results gave us guidelines for their clinical application.

Effects of carboxytherapy on skin laxity

“…However, when these data are statistically analyzed, they show no difference compared to the control group. This study corroborates Ahmed and Mostafa study13 who also observed an increase in the amount of longer elastic fibers, observing as well that these fibers were thicker and evenly disposed after intradermal CO 2 injection. However, these authors did not perform morphometric analysis.…”

“…Ahmed and Mostafa study 13 who also observed an increase in the amount of longer elastic fibers, observing as well that these fibers were thicker and evenly disposed after intradermal CO 2 injection.…”

“…No studies on morphometric evaluation after carboxytherapy application were found, except for histological analysis, in which the authors also found an increase in collagen 9,12,13…”

“…In the comparative study between carboxytherapy, platelet‐rich plasma (PRP), and radio frequency of Ahmed and Mostafa,13 carbon dioxide was administered with a 30G needle at flow rate of 50 mL min to provide 3 mL of CO 2 per mark in the stretch mark treatment, with an average time of 5‐9 minutes per session. Carbon dioxide was administered in the surface dermis in five sessions with an interval of 1 week.…”

“…No studies on morphometric evaluation after carboxytherapy application were found, except for histological analysis, in which the authors also found an increase in collagen. 9,12,13 F I G U R E 1 Effect of carboxytherapy treatment on picrosirius-stained human skin fibers. Skin of 32-year-old woman: was also used in the study.…”